Evidence map›Paper›PMID 36008881›Full record

ArticleJournal of biomedical optics2022

Difference imaging from single measurements in diffuse optical tomography: a deep learning approach.

Shuying Li, Menghao Zhang, Minghao Xue, Quing Zhu

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shuying LiWashington University in St. Louis, Optical and Ultrasound Imaging Lab, Department of Biomedical Engineering, St. Louis, Missouri, United States, United States.
Menghao ZhangWashington University in St. Louis, Optical and Ultrasound Imaging Lab, Department of Electrical and Systems Engineering, St. Louis, Missouri, United States, United States.
Minghao XueWashington University in St. Louis, Optical and Ultrasound Imaging Lab, Department of Biomedical Engineering, St. Louis, Missouri, United States, United States.
Quing ZhuWashington University in St. Louis, Optical and Ultrasound Imaging Lab, Department of Biomedical Engineering, St. Louis, Missouri, United States, United States.

Funding

Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical TomographyR01CA228047 · NCI · WASHINGTON UNIVERSITY · PI POPLACK, STEVEN, ZHU, QUING · 2019 to 2023
$1.9M
NCI NIH HHS R01 CA228047
6 · The paper itself

Abstract

significance"Difference imaging," which reconstructs target optical properties using measurements with and without target information, is often used in diffuse optical tomography (DOT) in vivo imaging. However, taking additional reference measurements is time consuming, and mismatches between the target medium and the reference medium can cause inaccurate reconstruction.

aimWe aim to streamline the data acquisition and mitigate the mismatch problems in DOT difference imaging using a deep learning-based approach to generate data from target measurements only. APPROACH: We train an artificial neural network to output data for difference imaging from target measurements only. The model is trained and validated on simulation data and tested with simulations, phantom experiments, and clinical data from 56 patients with breast lesions.

resultsThe proposed method has comparable performance to the traditional approach using measurements without mismatch between the target side and the reference side, and it outperforms the traditional approach using measurements when there is a mismatch. It also improves the target-to-artifact ratio and lesion localization in patient data.

conclusionsThe proposed method can simplify the data acquisition procedure, mitigate mismatch problems, and improve reconstructed image quality in DOT difference imaging.

Indexed as

Deep LearningTomography, OpticalAlgorithmsArtifactsHumansImage Processing, Computer-AssistedPhantoms, Imagingartificial neural networkbreast cancerdeep learningdiffuse optical tomography

Identifiers

PMID36008881
PMCPMC9403167

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.