Evidence map›Paper›PMID 36008616›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2022

Expert consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology on the determination of biomarkers in pancreatic and biliary tract cancer.

Ruth Vera, Carolina Ibarrola-de-Andrés, Jorge Adeva, Judith Pérez-Rojas, Pilar García-Alfonso, Yolanda Rodríguez-Gil, Teresa Macarulla, Teresa Serrano-Piñol, Rebeca Mondéjar, Beatriz Madrigal-Rubiales

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Current patterns of next-generation sequencing implementation in hepatocellular carcinoma in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Ruth VeraNavarra University Hospital, Spanish Society of Medical Oncology (SEOM), Calle Irunlarrea, 3, Navarra, 31008, Pamplona, Spain. ruth.vera.garcia@cfnavarra.es.ORCID http://orcid.org/0000-0003-1524-3147
Carolina Ibarrola-de-Andrés12 de Octubre University Hospital, Spanish Society of Pathology (SEAP), Madrid, Spain.
Jorge Adeva12 de Octubre University Hospital, Spanish Society of Medical Oncology (SEOM), Madrid, Spain.
Judith Pérez-RojasLa Fe University and Polytechnic Hospital, Spanish Society of Pathology (SEAP), Valencia, Spain.
Pilar García-AlfonsoGregorio Marañón University Hospital, Spanish Society of Medical Oncology (SEOM), Madrid, Spain.
Yolanda Rodríguez-Gil12 de Octubre University Hospital, Spanish Society of Pathology (SEAP), Madrid, Spain.
Teresa MacarullaVall d'Hebron University Hospital, Spanish Society of Medical Oncology (SEOM), Barcelona, Spain.
Teresa Serrano-PiñolBellvitge University Hospital, Spanish Society of Pathology (SEAP), Barcelona, Spain.
Rebeca MondéjarLa Princesa University Hospital, Spanish Society of Medical Oncology (SEOM), Madrid, Spain.
Beatriz Madrigal-RubialesRío Hortega University Hospital, Spanish Society of Pathology (SEAP), Valladolid, Spain.
Spanish Society of Hematology and Hemotherapy · ESBellvitge University Hospital · ESHospital General Universitario Gregorio Marañón · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Río Hortega · ESUniversidad de Navarra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer and biliary tract cancer have a poor prognosis. In recent years, the development of new diagnostic techniques has enabled the identification of the main genetic alterations involved in the development of these tumours. Multiple studies have assessed the ability of certain biomarkers, such as BRCA in pancreatic cancer, IDH1 or FGFR2 in biliary tract cancer and microsatellite instability or NTRK fusions in an agnostic tumour fashion, to predict response to treatment.In this consensus, a group of experts selected by the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP) reviewed the role played by these mutations in the process of carcinogenesis and their clinical implications. As a result, this article proposes a series of recommendations to optimize the determination of these biomarkers to help standardize the diagnosis and treatment of these tumours.

Indexed as

Biliary Tract NeoplasmsPancreatic NeoplasmsBiomarkers, TumorConsensusHumansMedical OncologyBiomarkers, TumorBiliary tract cancerMolecular diagnosisPancreatic cancerPredictive valuePrognostic valueTargeted therapies

Identifiers

PMID36008616
PMCPMC9522813
OpenAlexW4293240223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.