Evidence map›Paper›PMID 36008560›Full record

Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2023

Non-operative vs. operative treatment for multiple rib fractures after blunt thoracic trauma: a multicenter prospective cohort study.

Ruben J Hoepelman, Frank J P Beeres, Reinier B Beks, Arthur A R Sweet, Frank F Ijpma, Koen W W Lansink, Bas van Wageningen, Tjarda N Tromp, Björn-Christian Link, Nicole M van Veelen and 6 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Comparison of flail and multiple simple rib fracture patterns among patients included in rib fracture studies; A systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Guideline
  3. Preventing confounding in observational studies in orthopedic trauma surgery through expert panels: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  4. Review
  5. Article
  6. Review
  7. Review
  8. Demographics, treatment, and outcomes of rib fractures in older adults: a retrospective multi-institutional study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  9. Implant irritation and removal rates in operatively treated multiple rib fractures: a 49-month follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ruben J HoepelmanDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands. rjhoepelman@gmail.com.ORCID http://orcid.org/0000-0003-2298-244X
Frank J P BeeresDepartment of Orthopedic and Trauma Surgery, Luzerner Kantonsspital, Lucerne, Switzerland.
Reinier B BeksDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Arthur A R SweetDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Frank F IjpmaDepartment of Trauma Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Koen W W LansinkDepartment of Trauma Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
Bas van WageningenDepartment of Trauma Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Tjarda N TrompDepartment of Trauma Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Björn-Christian LinkDepartment of Orthopedic and Trauma Surgery, Luzerner Kantonsspital, Lucerne, Switzerland.
Nicole M van VeelenDepartment of Orthopedic and Trauma Surgery, Luzerner Kantonsspital, Lucerne, Switzerland.
Jochem M HoogendoornDepartment of Trauma Surgery, Haaglanden Medical Center, The Hague, The Netherlands.
Mirjam B de JongDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Mark C P van BaalDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Luke P H LeenenDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.
Rolf H H GroenwoldDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Roderick M HouwertDepartment of Surgery, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands.

Funding

DePuy Synthes DPS-TCMF-2017-036
6 · The paper itself

Abstract

backgroundPatients with multiple rib fractures without a clinical flail chest are increasingly being treated with rib fixation; however, high-quality evidence to support this development is lacking.

methodsWe conducted a prospective multicenter observational study comparing rib fixation to non-operative treatment in all patients aged 18 years and older with computed tomography confirmed multiple rib fractures without a clinical flail chest. Three centers performed rib fixation as standard of care. For adequate comparison, the other three centers performed only non-operative treatment. As such clinical equipoise formed the basis for the comparison in this study. Patients were matched using propensity score matching.

resultsIn total 927 patients with multiple rib fractures were included. In the three hospitals that performed rib fixation, 80 (14%) out of 591 patients underwent rib fixation. From the nonoperative centers, on average 71 patients were adequately matched to 71 rib fixation patients after propensity score matching. Rib fixation was associated with an increase in hospital length of stay (HLOS) of 4.9 days (95%CI 0.8-9.1, p = 0.02) and a decrease in quality of life (QoL) measured by the EQ5D questionnaire at 1 year of 0.1 (95% CI - 0.2-0.0, p = 0.035) compared to non-operative treatment. A subgroup analysis of patients who received operative care within 72 h showed a similar decrease in QoL. Up to 22 patients (28%) who underwent surgery experienced implant-related irritation.

conclusionsWe found no benefits and only detrimental effects associated with rib fixation. Based on these results, we do not recommend rib fixation as the standard of care for patients with multiple rib fractures.

trial registrationRegistered in the Netherlands Trial Register NTR6833 on 13/11/2017.

Indexed as

Flail ChestRib FracturesSpinal FracturesWounds, NonpenetratingFracture Fixation, InternalHumansLength of StayProspective StudiesQuality of LifeRetrospective StudiesMultiple rib fracturesNon-operative treatmentRib fixationRib fracture

Identifiers

PMID36008560
PMCPMC9925506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.