Evidence map›Paper›PMID 36008523›Full record

Observational studyScientific reports2022

Pulmonary pathophysiology development of COVID-19 assessed by serial Electrical Impedance Tomography in the MaastrICCht cohort.

Serge J H Heines, Bas C T van Bussel, Melanie J Acampo-de Jong, Frank C Bennis, Rob J J van Gassel, Rald V M Groven, Nanon F L Heijnen, Ben J M Hermans, René Hounjet, Johan van Koll and 10 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Monitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Serge J H HeinesDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands. s.heines@mumc.nl.ORCID 0000-0001-7672-4177
Bas C T van BusselDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0003-1621-7848
Melanie J Acampo-de JongDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Frank C BennisDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-6233-9101
Rob J J van GasselDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-0780-2052
Rald V M GrovenDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0001-8733-289X
Nanon F L HeijnenDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-9147-891X
Ben J M HermansDepartment of Physiology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-7780-4427
René HounjetDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Johan van KollDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Mark M G MulderDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-6485-8060
Marcel C G van de PollDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-3302-4063
Frank van RosmalenDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-9522-3711
Ruud SegersDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Sander SteynsDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Ulrich StrauchDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Jeanette TasDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-8914-0960
Iwan C C van der HorstDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0003-3891-8522
Sander M J van KuijkDepartment of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre+, Maastricht, The Netherlands.ORCID 0000-0003-2796-729X
Dennis C J J BergmansDepartment of Intensive Care, Maastricht University Medical Centre+, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.ORCID 0000-0002-4224-6426
Maastricht University Medical Centre · NLMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with SARS-CoV-2 infection present with different lung compliance and progression of disease differs. Measures of lung mechanics in SARS-CoV-2 patients may unravel different pathophysiologic mechanisms during mechanical ventilation. The objective of this prospective observational study is to describe whether Electrical Impedance Tomography (EIT) guided positive end-expiratory pressure (PEEP) levels unravel changes in EIT-derived parameters over time and whether the changes differ between survivors and non-survivors. Serial EIT-measurements of alveolar overdistension, collapse, and compliance change in ventilated SARS-CoV-2 patients were analysed. In 80 out of 94 patients, we took 283 EIT measurements (93 from day 1-3 after intubation, 66 from day 4-6, and 124 from day 7 and beyond). Fifty-one patients (64%) survived the ICU. At admission mean PaO

Indexed as

COVID-19Electric ImpedanceHumansPositive-Pressure RespirationSARS-CoV-2TomographyTomography, X-Ray Computed

Identifiers

PMID36008523
PMCPMC9403977
OpenAlexW4293102041

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.