ReviewNPJ microgravity2022
Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome.
Review in NPJ microgravity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Physiological cerebrospinal fluid interactions between brain and eye structures are altered after long-duration spaceflight.Experimental physiology · 2026Article
- Ophthalmic and Visual System Changes in Human Spaceflight: A Review of Mechanisms, Measurement, and Countermeasures.Journal of clinical medicine · 2026Review
- Prediction of Cerebrospinal Fluid (CSF) Pressure with Generative Adversarial Network Synthetic Plasma-CSF Biomarker Pairing.Neuroinformatics · 2025Article
- Impact of microgravity on retinal neuroimmune responses and visual dysfunction in rats.International journal of ophthalmology · 2025Article
- XR-SANS: a multi-modal framework for analyzing visual changes with extended reality (XR) in Spaceflight Associated Neuro-Ocular Syndrome (SANS).Eye (London, England) · 2024Article
- Precisional modulation of translaminar pressure gradients for ophthalmic diseases.European journal of ophthalmology · 2024Review
- Ocular immunology and inflammation under microgravity conditions and the pathogenesis of spaceflight associated neuro-ocular syndrome (SANS).Eye (London, England) · 2024Article
- Dynamic Visual Acuity, Vestibulo-Ocular Reflex, and Visual Field in National Football League (NFL) Officiating: Physiology and Visualization Engineering for 3D Virtual On-Field Training.Vision (Basel, Switzerland) · 2024Article
- Corneal abrasions in space: current therapeutics and future directions.Eye (London, England) · 2024Article
- Head-mounted display cataract surgery: a new frontier with eye tracking and foveated rendering technology.Eye (London, England) · 2024Article
- Ocular oxidative changes and antioxidant therapy during spaceflight.Eye (London, England) · 2024Article
- Anaemia, idiopathic intracranial hypertension (IIH) and spaceflight associated neuro-ocular syndrome (SANS).Eye (London, England) · 2024Article
- SANS-CNN: An automated machine learning technique for spaceflight associated neuro-ocular syndrome with astronaut imaging data.NPJ microgravity · 2024Article
- Space radiation and the potential for early cataract development.Eye (London, England) · 2024Article
- Advanced Visualization Engineering for Vision Disorders: A Clinically Focused Guide to Current Technology and Future Applications.Annals of biomedical engineering · 2024Review
- Navigating the Unknown: A Comprehensive Review of Spaceflight-Associated Neuro-Ocular Syndrome.Cureus · 2024Review
- Anatomical considerations for reducing ocular emergencies during spaceflight.Irish journal of medical science · 2024Review
- The future of ophthalmology and vision science with the Apple Vision Pro.Eye (London, England) · 2024Article
- Apple Vision Pro and the advancement of medical education with extended reality.Canadian medical education journal · 2024Article
- Chorioretinal folds in astronauts: risk of chorioretinal fold-related maculopathy and terrestrial staging of disease.Eye (London, England) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The neuro-ocular effects of long-duration spaceflight have been termed Spaceflight Associated Neuro-Ocular Syndrome (SANS) and are a potential challenge for future, human space exploration. The underlying pathogenesis of SANS remains ill-defined, but several emerging translational applications of terrestrial head-mounted, visual assessment technology and machine learning frameworks are being studied for potential use in SANS. To develop such technology requires close consideration of the spaceflight environment which is limited in medical resources and imaging modalities. This austere environment necessitates the utilization of low mass, low footprint technology to build a visual assessment system that is comprehensive, accessible, and efficient. In this paper, we discuss the unique considerations for developing this technology for SANS and translational applications on Earth. Several key limitations observed in the austere spaceflight environment share similarities to barriers to care for underserved areas on Earth. We discuss common terrestrial ophthalmic diseases and how machine learning and visual assessment technology for SANS can help increase screening for early intervention. The foundational developments with this novel system may help protect the visual health of both astronauts and individuals on Earth.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.