ArticleScientific reports2022
Resting-state functional connectivity does not predict individual differences in the effects of emotion on memory.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Prediction of cognitive test scores: a comparison of brain structure, health, demographic, and cognitive data across adulthood.GeroScience · 2026Article
- Fifteen years on: a review of the Cam-CAN study of the cognitive neuroscience of ageing.GeroScience · 2026Review
- Prediction of Verbal Abilities From Brain Connectivity Data Across the Lifespan Using a Machine Learning Approach.Human brain mapping · 2025Article
- Network and state specificity in connectivity-based predictions of individual behavior.Human brain mapping · 2024Article
- Network and State Specificity in Connectivity-Based Predictions of Individual Behavior.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 3 countries.
Funding
Abstract
Emotion-laden events and objects are typically better remembered than neutral ones. This is usually explained by stronger functional coupling in the brain evoked by emotional content. However, most research on this issue has focused on functional connectivity evoked during or after learning. The effect of an individual's functional connectivity at rest is unknown. Our pre-registered study addresses this issue by analysing a large database, the Cambridge Centre for Ageing and Neuroscience, which includes resting-state data and emotional memory scores from 303 participants aged 18-87 years. We applied regularised regression to select the relevant connections and replicated previous findings that whole-brain resting-state functional connectivity can predict age and intelligence in younger adults. However, whole-brain functional connectivity predicted neither an emotional enhancement effect (i.e., the degree to which emotionally positive or negative events are remembered better than neutral events) nor a positivity bias effect (i.e., the degree to which emotionally positive events are remembered better than negative events), failing to support our pre-registered hypotheses. These results imply a small or no association between individual differences in functional connectivity at rest and emotional memory, and support recent notions that resting-state functional connectivity is not always useful in predicting individual differences in behavioural measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.