Evidence map›Paper›PMID 36008179›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2024

Less is better? Comparing effects of median sternotomy and thoracotomy surgical approaches for left ventricular assist device implantation on postoperative outcomes and valvulopathy.

Alice Vinogradsky, Yuming Ning, Paul Kurlansky, Michael Kirschner, Melana Yuzefpolskaya, Paolo Colombo, Gabriel Sayer, Nir Uriel, Yoshifumi Naka, Koji Takeda

Open access · greenAbstract read
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Recent Developments in Ventricular Assist Device Therapy.Reviews in cardiovascular medicine · 2025
    Review
  4. Does lateral approach preserve the right ventricular function after HeartMate 3 insertion?Interdisciplinary cardiovascular and thoracic surgery · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alice VinogradskyDivision of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Yuming NingDepartment of Surgery, Center for Innovation and Outcomes Research, Columbia University Irving Medical Center, New York, NY.
Paul KurlanskyDepartment of Surgery, Center for Innovation and Outcomes Research, Columbia University Irving Medical Center, New York, NY.
Michael KirschnerDivision of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Melana YuzefpolskayaDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Paolo ColomboDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Gabriel SayerDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Nir UrielDivision of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Yoshifumi NakaDivision of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Koji TakedaDivision of Cardiac, Thoracic & Vascular Surgery, Department of Surgery, Columbia University Irving Medical Center, New York, NY. Electronic address: kt2485@cumc.columbia.edu.
Columbia University Irving Medical Center · USCenter for Innovation · US

Funding

SHORT-TERM TRAINING: STUDENTS IN PROFESSIONAL SCHOOLST35HL007616 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI RUDOLPH L LEIBEL, Markus Y Mapara · 1985 to 2026
$4.4M
NHLBI NIH HHS T35 HL007616
6 · The paper itself

Abstract

objectiveOur objective was to compare outcomes after left ventricular assist device implantation performed via median sternotomy or lateral thoracotomy.

methodsWe retrospectively analyzed 222 adult patients with the HeartMate3 (Abbott Lab) left ventricular assist device implanted between November 2014 and November 2021. Outcomes stratified by surgical approach were evaluated in propensity score-matched groups. The primary outcome was 1-year survival. Secondary outcomes included in-hospital morbidity and mortality, readmissions, and significant valvular regurgitation.

resultsOur cohort consisted of 60 patients (27%) who underwent lateral thoracotomy and 162 patients (73%) who underwent median sternotomy. Propensity score matching compared 45 patients who underwent lateral thoracotomy with 68 patients who underwent median sternotomy. There were no differences in intensive care unit or hospital stay duration (median, 10 vs 11 days, P = .58; 46 vs 40 days, P = .279), time to extubation (median, 2 days, P = .627), vasoactive-inotropic scores at intensive care unit arrival (18.20 vs 16.60, P = .654), or in-hospital mortality (2 [5%] vs 4 [6.1%] patients, P = 1). One-year survival (95.56% vs 90.61%, P = .48) and all-cause hospital readmission rate (Gray's test: P = .532) were also comparable. Patients who underwent lateral thoracotomy had significantly less early right ventricular failure (24.4% vs 53.7%, P = .004), although they had more follow-up tricuspid regurgitation (17.6% vs 0%, P = .030) and volume overload readmissions (Gray's test: P = .0005).

conclusionsOur data suggest that lateral thoracotomy is a safe although not necessarily superior alternative to median sternotomy for HeartMate 3 implantation in the perioperative and postoperative periods, because it precludes concomitant tricuspid valve repairs and may be associated with increased risk of late tricuspid regurgitation and volume overload readmissions.

Indexed as

Heart-Assist DevicesHeart FailureHeart Valve DiseasesTricuspid Valve InsufficiencyAdultHumansRetrospective StudiesSternotomyThoracotomyTreatment Outcomeconcomitant valve repairhemisternotomylateral thoracotomyleft ventricular assist deviceless invasivemedian sternotomytricuspid regurgitationvalvulopathy

Identifiers

PMID36008179
PMCPMC9669283
OpenAlexW4280543730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.