Evidence map›Paper›PMID 36008068›Full record

ArticleBMJ open2022

Burden, clinical features and outcomes of post-tuberculosis lung disease in sub-Saharan Africa: a protocol for a systematic review and meta-analysis.

Edwin Nuwagira, Joseph Baruch Baluku, David B Meya, Lisa Liang Philpotts, Mark J Siedner, Francis Bajunirwe, Stella G Mpagama, Peggy S Lai

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Edwin NuwagiraFaculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda edwinuwagira@gmail.com.ORCID 0000-0001-7526-9504
Joseph Baruch BalukuDivision of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda.
David B MeyaDepartment of Medicine, Makerere University Kampala, Kampala, Uganda.
Lisa Liang PhilpottsTreadwell Virtual Library, Massachusetts General Hospital, Boston, Massachusetts, UK.
Mark J SiednerDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Francis BajunirweDepartment of Community Health, Mbarara University of Science and Technology, Mbarara, Uganda.
Stella G MpagamaInfectious Diseases Unit, Tuberculosis Treatment Center Kibong'oto, Kilimanjaro, Tanzania.
Peggy S LaiDivision of Pulmonology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Massachusetts General Hospital · USMbarara University of Science and Technology · UGBoston Public Library · USKilimanjaro Christian Medical Centre · TZMakerere University · UG

Funding

Multi-morbidity in Uganda Research Capacity Initiative (MURCI) at Mbarara University of Science and TechnologyD43TW011632 · FIC · MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY · PI BAJUNIRWE, FRANCIS · 2020 to 2024
$1.2M
FIC NIH HHS D43 TW011632
6 · The paper itself

Abstract

introductionTuberculosis (TB) is significantly associated with multiple postinfectious, non-communicable diseases after microbiological cure. For example, those with a history of TB disease have a higher risk of developing chronic lung diseases at a younger age. However, the extent and nature of post-TB complications are not well described. Here, we present a protocol for a systematic review and meta-analysis, which aims to synthesise literature on the burden of post-TB lung disease (PTLD) in sub-Saharan Africa, describe phenotypes, long-term outcomes and the health-related quality of life of people with PTLD. METHODS AND ANALYSIS: A systematic search will be conducted using PubMed, EMBASE, Web of Science, African Journals Online and the Cochrane Library of Systematic Reviews. Papers published in English and French languages that report the prevalence, clinical features, quality of life and long-term outcomes of people with PTLD in sub-Saharan Africa will be considered. We will assess and critically appraise the methodological quality of all studies using the modified covidence. Qualitative and quantitative (network and meta-analysis) synthesis will be performed and STATA V.16 will be used to estimate the burden of PTLD. ETHICS AND DISSEMINATION: Ethical approval is not required for this systematic review and meta-analysis. Our results will be published in peer-reviewed journals. PROSPERO REGISTRATION NUMBER: CRD42021274018.

Indexed as

Lung DiseasesTuberculosisAfrica South of the SaharaHumansMeta-Analysis as TopicQuality of LifeSystematic Reviews as Topicpublic healththoracic medicinetuberculosis

Identifiers

PMID36008068
PMCPMC9422857
OpenAlexW4293239077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.