Evidence map›Paper›PMID 36008059›Full record

Trial reportBMJ open2022

Randomised clinical non-inferiority trial of breathing-based meditation and cognitive processing therapy for symptoms of post-traumatic stress disorder in military veterans.

Peter J Bayley, R Jay Schulz-Heik, Julia S Tang, Danielle C Mathersul, Tim Avery, Melinda Wong, Jamie M Zeitzer, Craig S Rosen, Adam S Burn, Beatriz Hernandez and 2 more

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02366403 nacompletednot on this map

Breathing Meditation Intervention for Post-Traumatic Stress Disorder

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2015 to 2020Enrolled85ConditionsStress Disorders, Post-TraumaticArmsSKY meditation, CPT-C
NCT06581523 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Feasibility and Efficacy Study of a Breathwork and Meditation Intervention (SKY Breath) on the Psychophysiological Well-Being of Individuals With Parkinson's Disease (iPD) and Their Care Partners

TypeinterventionalSponsorNova Southeastern UniversityRan2024 to 2026Enrolled40ConditionsParkinson's DiseaseArmsSKY Breath and Meditation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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  11. Social emotional learning and autonomic regulation enhance social connectedness in female adolescents with extensive exposure to adverse childhood experiences.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Peter J BayleyWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA Peter.Bayley@va.gov.
R Jay Schulz-HeikWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA.ORCID 0000-0002-2107-7125
Julia S TangWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA.
Danielle C MathersulPsychology, Murdoch University, Murdoch, Western Australia, Australia.ORCID 0000-0003-2372-8654
Tim AveryWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA.
Melinda WongWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA.
Jamie M ZeitzerDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Craig S RosenDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Adam S BurnWar Related Illness and Injury Study Center, VA Palo Alto Health Care System, Palo Alto, California, USA.
Beatriz HernandezDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Laura C LazzeroniDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Emma M SeppäläDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
VA Palo Alto Health Care System · USStanford University · USMurdoch University · AUNational Center for PTSD · USYale University · US

Funding

Breathing Meditation Intervention for Post Traumatic Stress DisorderI01RX001485 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI BAYLEY, PETER J. · 2015 to 2021
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RRD VA I01 RX001485
6 · The paper itself

Abstract

objectiveTest whether Sudarshan Kriya Yoga (SKY) was non-inferior to cognitive processing therapy (CPT) for treating symptoms of post-traumatic stress disorder (PTSD) among veterans via a parallel randomised controlled non-inferiority trial.

settingOutpatient Veterans Affairs healthcare centre.

participants85 veterans (75 men, 61% white, mean age 56.9) with symptoms of PTSD participated between October 2015 and March 2020: 59 participants completed the study.

interventionsSKY emphasises breathing routines and was delivered in group format in a 15-hour workshop followed by two 1-hour sessions per week for 5 weeks. CPT is an individual psychotherapy which emphasises shifting cognitive appraisals and was delivered in two 1-hour sessions per week for 6 weeks. MEASURES: The primary outcome measure was the PTSD Checklist-Civilian Version (PCL-C). The secondary measures were the Beck Depression Inventory-II (BDI-II) and Positive and Negative Affect Scale (PANAS).

resultsMean PCL-C at baseline was 56.5 (±12.6). Intent-to-treat analyses showed that PCL-C scores were reduced at 6 weeks (end of treatment) relative to baseline (SKY, -5.6,

conclusionsSKY may be non-inferior to CPT for treating symptoms of PTSD and merits further consideration as a treatment for PTSD. TRIAL REGISTRATION NUMBER: NCT02366403.

Indexed as

Cognitive Behavioral TherapyMeditationStress Disorders, Post-TraumaticVeteransYogaHumansMaleMiddle AgedTreatment OutcomeAnxiety disordersClinical trialsCOMPLEMENTARY MEDICINEDepression & mood disordersMENTAL HEALTH

Identifiers

PMID36008059
PMCPMC9422818
OpenAlexW4293239298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.