Evidence map›Paper›PMID 36008035›Full record

ArticleBiological psychiatry2022

Unmasking Schizophrenia: Synaptic Pruning in Adolescence Reveals a Latent Physiological Vulnerability in Prefrontal Recurrent Networks.

Matthew V Chafee, Bruno B Averbeck

Abstract read
In one paragraph

Article in Biological psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Synaptic dysfunction and adaptation after NMDA receptor ablation in the mouse medial prefrontal cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  7. Article
  8. Increased Brain-Age Gap in Young Adults With Psychotic Experiences.Biological psychiatry global open science · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew V ChafeeDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota. Electronic address: chafe001@umn.edu.
Bruno B AverbeckLaboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.

Funding

Frontal Striatal Systems and Dopamine in Normal and Pathological BehaviorZIAMH002928 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI AVERBECK, BRUNO · 2010 to 2025
$29.0M
Using a computational and network neuroscience framework to study pharmacological manipulations of state representation processes in early psychosisP50MH119569 · NIMH · UNIVERSITY OF MINNESOTA · PI A DAVID REDISH, Sophia Vinogradov · 2020 to 2026
$24.5M
Intramural NIH HHS ZIA MH002928NIMH NIH HHS P50 MH119569
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

SchizophreniaAdolescentHumansNeuronal PlasticityPrefrontal CortexSynapses

Identifiers

PMID36008035
PMCPMC9870034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.