Evidence map›Paper›PMID 36007595›Full record

Observational studyChest2023

Temporal Trends and Variation in Bronchoscopy Use for Acute Respiratory Failure in the United States.

Max T Wayne, Thomas S Valley, Douglas A Arenberg, Jose De Cardenas, Hallie C Prescott

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Chest, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Max T WayneDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, MI. Electronic address: maxtwayne@gmail.com.
Thomas S ValleyDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, MI; VA Center for Clinical Management Research, Ann Arbor, MI.
Douglas A ArenbergDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, MI.
Jose De CardenasDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, MI; Section of Thoracic Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI.
Hallie C PrescottDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ann Arbor, MI; VA Center for Clinical Management Research, Ann Arbor, MI.
Michigan Medicine · USVA Center for Clinical Management Research · US

Funding

Preventing avoidable deaths from pneumonia by improving use of intensive careK23HL140165 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VALLEY, THOMAS SEBASTIAN · 2018 to 2022
$915k
Rapid Understanding of Best Practices in Rural Intensive Care (RUBRIC)R01HS028038 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VALLEY, THOMAS SEBASTIAN · 2021 to 2022
$776k
AHRQ HHS R01 HS028038NHLBI NIH HHS K23 HL140165
6 · The paper itself

Abstract

backgroundNational data on bronchoscopy for the evaluation of acute respiratory failure are lacking, and the limited available data suggest wide variation in use. RESEARCH QUESTION: How commonly is bronchoscopy performed among hospitalizations with acute respiratory failure? How has use changed over time and across hospitals? STUDY DESIGN AND

methodsThis was an observational cohort study of adult hospitalizations (2012-2018) treated with invasive mechanical ventilation (IMV) using the National Inpatient Sample, which represents 97% of all hospitalizations in the United States. We measured the proportion of hospitalizations treated with IMV who underwent bronchoscopy and assessed trends in bronchoscopy use over time. Multilevel linear regression models were used to quantify hospital-level variation, adjusting for differences in patient and hospital characteristics.

resultsWe identified 6,101,070 IMV-treated hospitalizations (2012-2018), of whom 609,405 underwent bronchoscopy; among hospitalizations receiving bronchoscopy, mean age was 61 years, 41.8% were women, and in-hospital mortality was 30.8%. The percentage of IMV-treated hospitalizations receiving bronchoscopy increased from 9.5% (95% CI, 9.1%-9.9%) in 2012 to 10.8% (95% CI, 10.4%-11.2%) in 2018 (P < .001 for difference). In 2018, bronchoscopy use varied from 0% to 57.1% among 1,787 hospitals, and in multilevel models adjusted for patient and hospital characteristics, 16.0% of the variation was explained at the hospital level. The median OR was 2.13 (95% CI, 2.05-2.21), indicating 113% increased odds of receiving bronchoscopy if moving from a lower-use to a higher-use hospital.

interpretationBronchoscopy use among hospitalizations treated with IMV has increased over time. The large variation in use of bronchoscopy across hospitals suggests potentially unwarranted practice variation and need for further studies to clarify which patients benefit from bronchoscopy.

Indexed as

BronchoscopyRespiratory InsufficiencyAdultCohort StudiesFemaleHospital MortalityHumansMaleMiddle AgedRespiration, ArtificialRetrospective StudiesUnited Statesacute hypoxic respiratory failurebronchoscopyinvasive mechanical ventilation

Identifiers

PMID36007595
PMCPMC9859725
OpenAlexW4292633192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.