Evidence map›Paper›PMID 36007497›Full record

ArticleCerebrovascular diseases extra2022

Serum Prealbumin Levels on Admission as a Prognostic Marker in Stroke Patients Treated with Mechanical Thrombectomy.

Begoña López, Maria Castañón-Apilánez, Javier Molina-Gil, Santiago Fernández-Gordón Sánchez, Gemma González, Antía Reguera Acuña, Jose Maria Jimenez, Davinia Larrosa Campo, Montserrat González Delgado, Lorena Benavente-Fernández and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cerebrovascular diseases extra, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Begoña LópezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain, begolopezl@hotmail.com.
Maria Castañón-ApilánezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Javier Molina-GilDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Santiago Fernández-Gordón SánchezInstituto de Investigación Sanitaria Principado de Asturias, ISPA, Oviedo, Spain.
Gemma GonzálezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Antía Reguera AcuñaDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Jose Maria JimenezDepartment of Radiology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Davinia Larrosa CampoDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Montserrat González DelgadoDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Lorena Benavente-FernándezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Maria Rico-SantosDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Carmen García-CaboDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Sergio Calleja PuertaDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Elena López-CancioDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Hospital Universitario Central de Asturias · ESUniversidad de Oviedo · ESInstituto de Investigación Sanitaria del Principado de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrealbumin is a marker of malnutrition and inflammation. It has been associated with poor prognosis in cardiovascular disease, but less is known in stroke patients. Our objective was to evaluate the association of prealbumin levels at admission with prognosis in patients with stroke treated with mechanical thrombectomy.

methodsRetrospective study of a prospective database of consecutive patients treated with mechanical thrombectomy. Clinical, radiological, and blood parameters including serum prealbumin, and prognostic variables such as respiratory infection, in-hospital mortality, and the modified Rankin scale at 3 months were collected.

resultsWe included 319 patients between 2018 and 2019. Prealbumin levels were significantly lower in patients older than 80 years, women, patients with a prestroke Rankin score >2, a glomerular filtrate rate <60 mL/min, and in those with atrial fibrillation. Regarding prognostic variables, prealbumin levels were not associated with respiratory infection. Low prealbumin levels were associated with poor functional prognosis (Rankin score >2), in-hospital mortality, and 3-month mortality. In multivariate analysis, prealbumin was an independent risk factor associated with mortality at 3 months, OR 0.92 [0.86-0.98], p = 0.019.

conclusionLower prealbumin levels at admission behaved as an independent predictor of long-term mortality in patients treated with mechanical thrombectomy. These results should be replicated in other cohorts.

Indexed as

Brain IschemiaStrokeAged, 80 and overFemaleHumansPrealbuminPrognosisRetrospective StudiesThrombectomyTreatment OutcomePrealbuminAcute strokeMechanical thrombectomyModified Rankin scaleMortalityPrealbumin

Identifiers

PMID36007497
PMCPMC9941761
OpenAlexW4293072772

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.