Evidence map›Paper›PMID 36007432›Full record

ReviewThe American journal of emergency medicine2022

Toxicity of abortifacients: A review for physicians in the post roe era.

Maryann Mazer-Amirshahi, Peggy Ye

Abstract readReview
PubMed Publisher
In one paragraph

Review in The American journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. ACMT Position Statement: Position on the Recent Judicial Challenge of U.S. Food and Drug Administration Approval of Mifepristone.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2023
    Article
  2. Self-managed abortion: Toxic legislation, non-toxic medication.The American journal of emergency medicine · 2023
    Article
  3. Tetanus Infection Complicating an Unsafe Abortion with Resulting Maternal Mortality: A Case Report.Nigerian medical journal : journal of the Nigeria Medical Association
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Maryann Mazer-AmirshahiDepartment of Emergency Medicine, MedStar Washington Hospital Center, Washington, DC, United States of America; Georgetown University School of Medicine, Washington, DC, United States of America. Electronic address: maryannmazer@gmail.com.
Peggy YeGeorgetown University School of Medicine, Washington, DC, United States of America; Department of Obstetrics and Gynecology, MedStar Washington Hospital Center, Washington, DC, United States of America.
Georgetown University · USMedStar Washington Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOn June 24, 2022, the Supreme Court overturned Roe v. Wade, which will limit legal abortion in many areas of the U.S. Over half of abortions in the U.S. are performed using medication as opposed to surgical techniques. With widespread access to agents that are used for medication abortion, there may be an increase in emergency department presentations related to improper or unsupervised use of these medications.

methodsThis narrative review focuses on the contraindications, adverse effects, and toxicities of the most common agents used for medication abortion in the U.S.

resultsMedications included in this review are mifepristone, misoprostol, and methotrexate. Each of these medications has a unique adverse effect and toxicity profile.

conclusionAgents used for medication abortion have unique contraindications and adverse effects. Improper or unsupervised use may occur in the setting of limited abortion access and emergency medicine physicians are on the front lines in managing these presentations.

Indexed as

Abortifacient AgentsAbortion, InducedMisoprostolPhysiciansFemaleHumansMethotrexateMifepristonePregnancyUnited StatesAbortifacient AgentsMethotrexateMifepristoneMisoprostolEmergency departmentMedication abortionToxicity

Identifiers

PMID36007432
OpenAlexW4292476216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.