ArticleMolecular and cellular biology1987
Developmental-stage-specific expression of the hsp70 gene family during differentiation of the mammalian male germ line.
Article in Molecular and cellular biology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 111 citations in OpenAlex.
- Mechanisms of Hormonal, Genetic, and Temperature Regulation of Germ Cell Proliferation, Differentiation, and Death During Spermatogenesis.Biomolecules · 2025Review
- Histological and Transcriptomic Changes in Male Zebrafish Testes Due to Early Life Exposure to Low Level 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.Zebrafish · 2016Article
- Expression, function, and regulation of the testis-enriched heat shock HSPA2 gene in rodents and humans.Cell stress & chaperones · 2015Review
- Identification of a testis-enriched heat shock protein and fourteen members of Hsp70 family in the swamp eel.PloS one · 2013Article
- The 'omics revolution and our understanding of sperm cell biology.Asian journal of andrology · 2011Review
- Intracellular localization of constitutive and inducible heat shock protein 70 in rat liver after in vivo heat stress.Molecular and cellular biochemistry · 2004Article
- Structure of the 5' region of the Hst70 gene transcription unit: presence of an intron and multiple transcription initiation sites.The Biochemical journal · 2001Article
- Chaperones in cell cycle regulation and mitogenic signal transduction: a review.Cell proliferation · 2000Review
- Induction by prostaglandin A1 of haem oxygenase in myoblastic cells: an effect independent of expression of the 70 kDa heat shock protein.The Biochemical journal · 1995Article
- Complex expression of murine heat shock transcription factors.Nucleic acids research · 1995Article
- Genetic aspects of the hsp70 multigene family in vertebrates.Experientia · 1994Review
- Analysis of the mouse protamine 1 promoter in transgenic mice.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- The disappearance of an hsc70 species in mung bean seed during germination: purification and characterization of the protein.Plant molecular biology · 1993Article
- Mammalian heat shock protein families. Expression and functions.Experientia · 1992Review
- List of cloned mouse genes with unique expression patterns during spermatogenesis.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Article
- Surprising features of transcriptional regulation of heat shock genes.Gene expression · 1991Review
- Tissue-specific expression from a compound TATA-dependent and TATA-independent promoter.Molecular and cellular biology · 1990Article
- Characterization and inducibility of hsp 70 proteins in the male mouse germ line.The Journal of cell biology · 1990Article
- Experimental allergic orchitis in mice. VI. Recombinations within the H-2S/H-2D interval define the map position of the H-2-associated locus controlling disease susceptibility.Immunogenetics · 1990Article
- Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response.Molecular and cellular biology · 1989Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Mouse somatic tissues contain low levels of transcripts homologous to the heat shock-inducible and cognate members of the heat shock protein 70 (hsp70) gene family. An abundant, unique sized hsp70 mRNA of 2.7 kilobases (kb) is present in testes in the absence of exogenous stress. Its expression is restricted to germ cells and is developmentally regulated. The 2.7-kb transcript first appears during the haploid phase of spermatogenesis and is stable throughout the morphogenic stages of spermiogenesis. A 2.7-kb hsp70 mRNA is present in rat and human testes. These observations suggest that a member of the hsp70 gene family plays a role in the development of the mammalian male germ cell lineage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.