Evidence map›Paper›PMID 36006434›Full record

ArticleExperimental brain research2022

Postural support requirements preferentially modulate late components of the gastrocnemius response to transcranial magnetic stimulation.

Cassandra Russell, Nathan Difford, Alexander Stamenkovic, Paul Stapley, Darryl McAndrew, Caitlin Arpel, Colum MacKinnon, Jonathan Shemmell

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental brain research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Cassandra RussellSchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia.ORCID http://orcid.org/0000-0002-5485-3514
Nathan DiffordSchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia.
Alexander StamenkovicDepartment of Physical Therapy, College of Health Professions, Virgina Commonwealth University, Richmond, USA.
Paul StapleySchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia.
Darryl McAndrewSchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia.
Caitlin ArpelSchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia.
Colum MacKinnonDepartment of Neurology, University of Minnesota, Minneapolis, USA.
Jonathan ShemmellSchool of Medical, Indigenous and Health Sciences, Faculty of Science, Medicine and Health, University of Wollongong, Building 41, Northfields Avenue, Wollongong, NSW, 2522, Australia. shemmell@uow.edu.au.
University of Wollongong · AUUniversity of Minnesota · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mounting evidence suggests that motor evoked potentials (MEPs) recorded in upper limb muscles with postural support roles following transcranial magnetic stimulation receive contributions from both corticospinal and non-corticospinal descending pathways. We tested the hypothesis that neural structures responsible for regulating upright balance are involved in transmitting late portions of TMS-induced MEPs in a lower limb muscle. MEPs were recorded in the medial gastrocnemius muscles of each leg, while participants supported their upright posture in five postural conditions that required different levels of support from the target muscles. We observed that early and late portions of the MEP were modulated independently, with early MEP amplitude being reduced when high levels of postural support were required from a target muscle. Independent modulation of early and late MEPs by altered postural demand suggests largely separable transmission of each part of the MEP. The early component of the MEP is likely generated by fast-conducting corticospinal pathways, whereas the later component may be primarily transmitted along a polysynaptic cortico-reticulospinal pathway.

Indexed as

Pyramidal TractsTranscranial Magnetic StimulationElectromyographyEvoked Potentials, MotorHumansMuscle, SkeletalUpper ExtremityBalance controlBrainstemCortico-reticulospinalCorticospinalPostureReticular formationTriceps surae

Identifiers

PMID36006434
PMCPMC9510120
OpenAlexW4293092610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.