Evidence map›Paper›PMID 36006400›Full record

ArticleJournal of the American Chemical Society2022

A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids.

Jeff K Kerkovius, Andrea Stegner, Aneta Turlik, Pik Hoi Lam, Kendall N Houk, Sarah E Reisman

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Azine Dearomatization in Natural Product Total Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Oxidative Dearomatization of Pyridines.Journal of the American Chemical Society · 2024
    Article
  13. Article
  14. 1,2-Redox Transpositions of Tertiary Amides.Journal of the American Chemical Society · 2023
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeff K KerkoviusDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California91125, United States.ORCID 0000-0001-5692-0285
Andrea StegnerDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California91125, United States.ORCID 0000-0001-9408-3967
Aneta TurlikDepartmentof Chemistry and BiochemistryUniversity of California, Los Angeles, Los Angeles, California90095, United States.ORCID 0000-0002-0907-8969
Pik Hoi LamDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California91125, United States.
Kendall N HoukDepartmentof Chemistry and BiochemistryUniversity of California, Los Angeles, Los Angeles, California90095, United States.ORCID 0000-0002-8387-5261
Sarah E ReismanDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California91125, United States.ORCID 0000-0001-8244-9300

Funding

Chemical Synthesis of Chiral Bioactive MoleculesR35GM118191 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Sarah Elizabeth Reisman · 2016 to 2026
$6.6M
Computational Investigations of Asymmetric Carbon-Carbon Bond FormationF32GM134709 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TURLIK, ANETA · 2021 to 2022
$90k
NIGMS NIH HHS F32 GM134709NIGMS NIH HHS R35 GM118191
6 · The paper itself

Abstract

(+)-Matrine and (+)-isomatrine are tetracyclic alkaloids isolated from the plant

Indexed as

AlkaloidsSophoraMatrinesPiperidinesPyridinesQuinolizinesAlkaloidsMatrinesPiperidinesPyridinesQuinolizines

Identifiers

PMID36006400
PMCPMC10249042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.