Trial reportToxins2022
Effect of Botulinum Toxin Injection on EMG Activity and Bite Force in Masticatory Muscle Disorder: A Randomized Clinical Trial.
Trial report in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pooled it
- Botulinum Toxin Type A for Myogenous Temporomandibular Disorders, Focusing on the Duration of Clinical Effects and Dosage Parameters: A Systematic Review.Head & face medicine · 2026Pooled it
- What Happened to Masticatory Muscles after Botulinum-Toxin-Type A Injection into Masseter: A Systematic Review.Aesthetic plastic surgery · 2026Pooled it
- Botulinum Toxin for Bruxism: An Overview.Toxins · 2025Pooled it
- Effects of Botulinum Toxin Injection on Masticatory Muscle Activity in Sleep Bruxism: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Masseter Muscle Morphometric Changes After Botulinum Toxin Type A Injection: A Prospective 3-Month Study.Toxins · 2026Observational
- Longitudinal Assessment of Masseter Muscle Elasticity Changes After BoNT-A Injection Using Ultrasound Elastography: A Prospective Self-Controlled Study.Aesthetic plastic surgery · 2026Article
- A Clinical Decision-Making Algorithm for Botulinum Toxin Use in Temporomandibular Disorders and Bruxism.Journal of clinical medicine · 2026Article
- Central and Peripheral Sensitization in Temporomandibular Disorders: Proposed Mechanisms of Botulinum Toxin Therapy.Toxins · 2026Review
- Dental publications on the treatment of temporomandibular disorders: A bibliometric analysis.F1000Research · 2026Review
- Review
- Analysis of the Use of Sample Size and Effect Size Calculations in a Temporomandibular Disorders Randomised Controlled Trial-Short Narrative Review.Journal of personalized medicine · 2024Review
- Comparative Study on the Duration and Efficacy of Various Botulinum Toxin Type A Injections for Reducing Masseteric Muscle Bite Force and Treating Facial Wrinkles.Dermatology and therapy · 2024Article
- Surface Electromyography in Dentistry-Past, Present and Future.Journal of clinical medicine · 2024Review
- Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis-A Randomized Pilot Study.Muscles (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Botulinum toxin type A (BoNT-A) is increasingly used in treating masticatory muscle pain disorder; however, safe doses and reinjection intervals still need to be established. The purpose of this randomized clinical trial was to evaluate the degree and duration of the impairment of masticatory muscle performance. Fifty-seven subjects were randomly divided into two groups: one of which received BoNT-A first (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.