Evidence map›Paper›PMID 36006107›Full record

ArticleToxics2022

Boron Compounds Exhibit Protective Effects against Aluminum-Induced Neurotoxicity and Genotoxicity: In Vitro and In Vivo Study.

Hasan Turkez, Serkan Yıldırım, Elvan Sahin, Mehmet Enes Arslan, Bugrahan Emsen, Ozlem Ozdemir Tozlu, Gonca Alak, Arzu Ucar, Abdulgani Tatar, Ahmet Hacimuftuoglu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Hasan TurkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0002-7046-8990
Serkan YıldırımDepartment of Pathology, Faculty of Veterinary, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0003-2457-3367
Elvan SahinDepartment of Histology and Embryology, Faculty of Medicine, Sakarya University, 54050 Sakarya, Turkey.ORCID 0000-0001-8585-9903
Mehmet Enes ArslanDepartment of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, 25050 Erzurum, Turkey.ORCID 0000-0002-1600-2305
Bugrahan EmsenDepartment of Biology, Kamil Özdağ Faculty of Science, Karamanoğlu Mehmetbey University, 70200 Karaman, Turkey.ORCID 0000-0002-9636-2596
Ozlem Ozdemir TozluDepartment of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, 25050 Erzurum, Turkey.ORCID 0000-0002-5472-8174
Gonca AlakDepartment of Aquaculture, Faculty of Fisheries, Atatürk University, 25240 Erzurum, Turkey.
Arzu UcarDepartment of Aquaculture, Faculty of Fisheries, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0001-5675-9401
Abdulgani TatarDepartment of Medical Genetics, Medical Faculty, Atatürk University, 25240 Erzurum, Turkey.
Ahmet HacimuftuogluDepartment of Medical Pharmacology, Medical Faculty, Atatürk University, 25240 Erzurum, Turkey.
Mevlut Sait KelesDepartment of Biochemistry, Medical Faculty, Uskudar University, 34664 Istanbul, Turkey.ORCID 0000-0002-4905-219X
Fatime GeyikogluDepartment of Biology, Faculty of Arts and Sciences, Atatürk University, 25240 Erzurum, Turkey.
Muhammed AtamanalpDepartment of Aquaculture, Faculty of Fisheries, Atatürk University, 25240 Erzurum, Turkey.ORCID 0000-0002-2038-3921
Fatih SaruhanDepartment of Medical Pharmacology, Medical Faculty, Atatürk University, 25240 Erzurum, Turkey.
Adil MardinogluScience for Life Laboratory, KTH-Royal Institute of Technology, 114 28 Stockholm, Sweden.ORCID 0000-0002-4254-6090
Atatürk University · TRErzurum Technical University · TRKaramanoğlu Mehmetbey University · TRKing's College London · GBSakarya University · TRÜsküdar University · TR

Funding

The National Boron Research Institute (BOREN) Ç256
6 · The paper itself

Abstract

Genetic, neuropathological and biochemical investigations have revealed meaningful relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage. Hence, intensive efforts are being made to minimize the harmful effects of Al. Moreover, boron compounds are used in a broad mix of industries, from cosmetics and pharmaceuticals to agriculture. They affect critical biological functions in cellular events and enzymatic reactions, as well as endocrinal and mineral metabolisms. There are limited dose-related data about boric acid (BA) and other boron compounds, including colemanite (Col), ulexite (UX) and borax (BX), which have commercial prominence. In this study, we evaluate boron compounds' genetic, cytological, biochemical and pathological effects against aluminum chloride (AlCl

Indexed as

aluminum chloridebloodboron compoundsbraincytotoxicitygenotoxicityhematotoxicityhistopathologyneurotoxicityoxidative status

Identifiers

PMID36006107
PMCPMC9413983
OpenAlexW4288722956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.