Evidence map›Paper›PMID 36005900›Full record

ArticleImmunology and cell biology2022

METTL3 inhibition reduces N

Shuang Li, Dawei Zou, Wenhao Chen, Gavin W Britz, Zhaoqian Liu, Yi-Lan Weng

Open access · greenAbstract read
In one paragraph

Article in Immunology and cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  3. Article
  4. NNature reviews. Cancer · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. METTL3-mediated mMolecular biology reports · 2025
    Review
  9. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Role and regulators of NFrontiers in pharmacology · 2024
    Review
  15. Review
  16. NBiology · 2023
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shuang LiDepartment of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Dawei ZouDepartment of Surgery, Immunobiology & Transplant Science Center, Houston Methodist Research Institute and Institute for Academic Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Wenhao ChenDepartment of Surgery, Immunobiology & Transplant Science Center, Houston Methodist Research Institute and Institute for Academic Medicine, Houston Methodist Hospital, Houston, Texas, USA.
Gavin W BritzDepartment of Neurosurgery, Houston Methodist Neurological Institute, Houston, Texas, USA.
Zhaoqian LiuDepartment of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, and National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yi-Lan WengDepartment of Neurosurgery, Houston Methodist Neurological Institute, Houston, Texas, USA.ORCID 0000-0001-6175-0401
Houston Methodist · USCentral South University · CN

Funding

Systems-wide analysis of oxidative stress-responsive m6A epitranscriptomeR01ES031511 · NIEHS · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WENG, YI-LAN · 2020 to 2025
$2.0M
NIEHS NIH HHS R01 ES031511NIEHS NIH HHS R01ES031511
6 · The paper itself

Abstract

Alloreactive CD4

Indexed as

CD4-Positive T-LymphocytesHematopoietic Stem Cell TransplantationMethyltransferasesAdenosineAnimalsAntibodies, MonoclonalCD28 AntigensCD8-Positive T-LymphocytesGraft RejectionIsoantigensKi-67 AntigenMiceMice, Inbred BALB CMice, Inbred C57BLRNATranscription FactorsAdenosineAntibodies, MonoclonalCD28 AntigensIsoantigensKi-67 AntigenMethyltransferasesMettl3 protein, mouseN-methyladenosineRNATranscription FactorsAllogeneic responseMETTL3N6-methyladenosineSTM2457T cells

Identifiers

PMID36005900
PMCPMC9990421
OpenAlexW4293088786

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.