ArticleRheumatology (Oxford, England)2023
Standardized nailfold capillaroscopy in children with rheumatic diseases: a worldwide study.
Article in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The 2024 British Society for Rheumatology guideline for management of systemic sclerosis.Rheumatology (Oxford, England) · 2024Guideline
- Juvenile Systemic Sclerosis in a Single Center: Clinical Features, Capillaroscopic Findings, Immunological Profile, and Treatment Outcomes-A Retrospective Descriptive Analysis.Children (Basel, Switzerland) · 2026Article
- Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity.Clinical and translational medicine · 2026Article
- Nailfold Capillary Morphology as a Potential Biomarker of Cardiovascular or Metabolic Risk in Children Aged 3-17 Years Prenatally Exposed to Alcohol.Alcohol, clinical & experimental research · 2026Article
- Nailfold Capillaroscopic Changes in Children with Atopic Dermatitis.Journal of clinical medicine · 2026Article
- Nailfold Videocapillaroscopy in Pediatric Rheumatology: Established Roles, Emerging Applications, and Future Perspectives.Balkan medical journal · 2026Review
- Phenotype-associated microvascular differences in pediatric Behçet's disease revealed by nailfold videocapillaroscopy.European journal of pediatrics · 2026Article
- Are we ready to predict progressive disease in juvenile systemic sclerosis?Journal of scleroderma and related disorders · 2026Article
- Revealing Microvascular Involvement in Pediatric Localized Scleroderma Through Nailfold Capillaroscopy.Children (Basel, Switzerland) · 2025Article
- Evaluation of Nailfold Capillaroscopic Findings in Pediatric Patients with Celiac Disease: A Cross-Sectional and Comparative Study.Diagnostics (Basel, Switzerland) · 2025Article
- Expert Perspective: Diagnostic Approach to Differentiating Juvenile Dermatomyositis From Muscular Dystrophy.Arthritis & rheumatology (Hoboken, N.J.) · 2025Article
- Metabolic consequences and nailfold capillary changes in children with familial Mediterranean fever.Italian journal of pediatrics · 2025Article
- Nailfold capillaroscopic assessment in pediatric patients with autoimmune uveitis: a case-control study.Clinical rheumatology · 2024Article
- Microvascular status in juvenile Sjögren's disease: the first nailfold videocapillaroscopy investigation.Clinical rheumatology · 2024Article
- Involvement of the systemic microcirculation in pediatric uveitis.Pediatric rheumatology online journal · 2023Article
- Automated Stabilization, Enhancement and Capillaries Segmentation in Videocapillaroscopy.Sensors (Basel, Switzerland) · 2023Article
- Correlations between capillary density and degree of skin pigmentation in healthy children analysed by nailfold video capillaroscopy.Quantitative imaging in medicine and surgery · 2023Article
- Associations between nailfold capillary aberrations and autoantibodies in children and adults with Raynaud's phenomenon.RMD open · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
33 authors at 18 institutions in 11 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo standardly assess and describe nailfold videocapillaroscopy (NVC) assessment in children and adolescents with juvenile rheumatic and musculoskeletal diseases (jRMD) vs healthy controls (HCs). MATERIAL AND
methodsIn consecutive jRMD children and matched HCs from 13 centres worldwide, 16 NVC images per patient were acquired locally and read centrally per international consensus standard evaluation of the EULAR Study Group on Microcirculation in Rheumatic Diseases. A total of 95 patients with JIA, 22 with JDM, 20 with childhood-onset SLE (cSLE), 13 with juvenile SSc (jSSc), 21 with localized scleroderma (lSc), 18 with MCTD and 20 with primary RP (PRP) were included. NVC differences between juvenile subgroups and HCs were calculated through multivariable regression analysis.
resultsA total of 6474 images were assessed from 413 subjects (mean age 12.1 years, 70.9% female). The quantitative NVC characteristics were significantly lower or higher in the following subgroups compared with HCs: for density: lower in jSSc, JDM, MCTD, cSLE and lSc; for dilations: higher in jSSc, MCTD and JDM; for abnormal shapes: higher in JDM and MCTD; for haemorrhages: higher in jSSc, MCTD, JDM and cSLE. The qualitative NVC assessment of JIA, lSc and PRP did not differ from HCs, whereas the cSLE and jSSc, MCTD, JDM and cSLE subgroups showed more non-specific and scleroderma patterns, respectively.
conclusionsThis analysis resulted from a pioneering registry of NVC in jRMD. The NVC assessment in jRMD differed significantly from HCs. Future prospective follow-up will further elucidate the role of NVC in jRMD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.