Evidence map›Paper›PMID 36005524›Full record

ReviewMarine drugs2022

Antioxidant Potential of Sea Cucumbers and Their Beneficial Effects on Human Health.

Abul Hossain, Deepika Dave, Fereidoon Shahidi

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
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  9. Hepatorenal protective role of encapsulatedJournal of advanced veterinary and animal research · 2026
    Article
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  17. Metabolomic profiling ofComputational and structural biotechnology journal · 2025
    Article
  18. Review
  19. Effect ofMolecules (Basel, Switzerland) · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abul HossainDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0002-7519-8555
Deepika DaveDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0003-4358-3181
Fereidoon ShahidiDepartment of Biochemistry, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.ORCID 0000-0002-9912-0330
Memorial University of Newfoundland · CA

Funding

Natural Sciences and Engineering Research Council RGPIN-2015-06121Natural Sciences and Engineering Research Council RGPIN-2016-04468
6 · The paper itself

Abstract

Sea cucumbers are considered a luxury food item and used locally in traditional medication due to their impressive nutritional profile and curative effects. Sea cucumbers contain a wide range of bioactive compounds, namely phenolics, polysaccharides, proteins (collagen and peptides), carotenoids, and saponins, demonstrating strong antioxidant and other activities. In particular, phenolic compounds, mainly phenolic acids and flavonoids, are abundant in this marine invertebrate and exhibit antioxidant activity. Protein hydrolysates and peptides obtained from sea cucumbers exhibit antioxidant potential, mainly dependent on the amino acid compositions and sequences as well as molecular weight, displayed for those of ≤20 kDa. Moreover, the antioxidant activity of sea cucumber polysaccharides, including fucosylated chondroitin sulfate and fucan, is a combination of numerous factors and is mostly associated with molecular weight, degree of sulfation, and type of major sugars. However, the activity of these bioactive compounds typically depends on the sea cucumber species, harvesting location, food habit, body part, and processing methods employed. This review summarizes the antioxidant activity of bioactive compounds obtained from sea cucumbers and their by-products for the first time. The mechanism of actions, chemical structures, and factors affecting the antioxidant activity are also discussed, along with the associated health benefits.

Indexed as

SaponinsSea CucumbersAnimalsAntioxidantsHumansInvertebratesPolysaccharidesAntioxidantsPolysaccharidesSaponinsantioxidantscarotenoidsphenolics and polyphenolicspolysaccharidesprotein hydrolysates and peptidessea cucumber

Identifiers

PMID36005524
PMCPMC9410154
OpenAlexW4293105016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.