Evidence map›Paper›PMID 36005520›Full record

ArticleMarine drugs2022

Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens.

Victoria N Safronova, Ilia A Bolosov, Roman N Kruglikov, Olga V Korobova, Eugenia S Pereskokova, Alexander I Borzilov, Pavel V Panteleev, Tatiana V Ovchinnikova

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Victoria N SafronovaM. M. Shemyakin & Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Miklukho-Maklaya Str., 16/10, 117997 Moscow, Russia.
Ilia A BolosovM. M. Shemyakin & Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Miklukho-Maklaya Str., 16/10, 117997 Moscow, Russia.
Roman N KruglikovM. M. Shemyakin & Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Miklukho-Maklaya Str., 16/10, 117997 Moscow, Russia.
Olga V KorobovaState Research Center for Applied Microbiology & Biotechnology (SRCAMB), 142279 Obolensk, Russia.
Eugenia S PereskokovaState Research Center for Applied Microbiology & Biotechnology (SRCAMB), 142279 Obolensk, Russia.
Alexander I BorzilovState Research Center for Applied Microbiology & Biotechnology (SRCAMB), 142279 Obolensk, Russia.ORCID 0000-0001-6309-7645
Pavel V PanteleevM. M. Shemyakin & Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Miklukho-Maklaya Str., 16/10, 117997 Moscow, Russia.ORCID 0000-0001-8448-031X
Tatiana V OvchinnikovaM. M. Shemyakin & Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, The Russian Academy of Sciences, Miklukho-Maklaya Str., 16/10, 117997 Moscow, Russia.ORCID 0000-0002-5950-249X
Institute of Bioorganic Chemistry · RUState Research Center for Applied Microbiology and Biotechnology · RULomonosov Moscow State University · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2021-1049
6 · The paper itself

Abstract

In recent years, new antibiotics targeting multidrug resistant Gram-negative bacteria have become urgently needed. Therefore, antimicrobial peptides are considered to be a novel perspective class of antibacterial agents. In this study, a panel of novel BRICHOS-related β-hairpin antimicrobial peptides were identified in transcriptomes of marine polychaeta species. Two of them-abarenicin from

Indexed as

PolychaetaAnimalsAnti-Bacterial AgentsBacteriaBiofilmsGram-Negative BacteriaMammalsMiceMicrobial Sensitivity TestsPeptidesAnti-Bacterial AgentsPeptidesabarenicinantibiofilm activityantimicrobial peptideantimicrobial resistanceBRICHOS domainmice modelpolychaeta

Identifiers

PMID36005520
PMCPMC9410094
OpenAlexW4291449535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.