Evidence map›Paper›PMID 36005514›Full record

ArticleMarine drugs2022

Fluorescently Labeled α-Conotoxin TxID, a New Probe for α3β4 Neuronal Nicotinic Acetylcholine Receptors.

Meiling Huang, Xiaopeng Zhu, Yishuai Yang, Yao Tan, Sulan Luo, Dongting Zhangsun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meiling HuangKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Life Sciences, Hainan University, Haikou 570228, China.
Xiaopeng ZhuMedical School, Guangxi University, Nanning 530004, China.ORCID 0000-0001-8830-4954
Yishuai YangKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Life Sciences, Hainan University, Haikou 570228, China.
Yao TanMedical School, Guangxi University, Nanning 530004, China.
Sulan LuoKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Life Sciences, Hainan University, Haikou 570228, China.ORCID 0000-0002-9358-5970
Dongting ZhangsunKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Life Sciences, Hainan University, Haikou 570228, China.
Guangxi University · CNHainan University · CN

Funding

Guangxi Science and Technology Base & Talents Fund GUIKE AD22035948National Natural Science Foundation of China 41966003 & 81872794
6 · The paper itself

Abstract

Neuronal nicotinic acetylcholine receptors (nAChRs) are important ion channel membrane proteins that are widely distributed in the central nervous system (CNS) and peripheral nervous system (PNS). As an important member, α3β4 nAChRs are related to pain sensation in PNS and nicotine addiction in CNS. However, research related to the α3β4 nAChRs is greatly limited by the lack of subtype-selective pharmacological tools. The α-conotoxin (α-CTx) TxID from the marine cone snail,

Indexed as

ConotoxinsConus SnailReceptors, NicotinicAnimalsNicotinic AntagonistsPatch-Clamp TechniquesConotoxinsNicotinic AntagonistsReceptors, Nicotinicapplicationfluorescent probetwo-electrode voltage clampα3β4 nAChRα-Conotoxin TxID

Identifiers

PMID36005514
PMCPMC9410468
OpenAlexW4291449577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.