Evidence map›Paper›PMID 36005504›Full record

ReviewMarine drugs2022

Marine Arthropods as a Source of Antimicrobial Peptides.

Juan Pablo Saucedo-Vázquez, Fernando Gushque, Nelson Santiago Vispo, Jenny Rodriguez, Marco Esteban Gudiño-Gomezjurado, Fernando Albericio, Markus P Tellkamp, Frank Alexis

Abstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. ScymicrosinFrontiers in microbiology · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. The Expression of Antibacterial Peptide Turgencin A inMolecules (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Transcriptomic Signature of Horseshoe CrabCurrent issues in molecular biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan Pablo Saucedo-VázquezCATS Research Group, School of Chemical Sciences & Engineering, Yachay Tech University, Hda. San José s/n y Proyecto Yachay, Urcuquí 100119, Ecuador.ORCID 0000-0002-4314-6363
Fernando GushqueSchool of Biological Sciences & Engineering, Yachay Tech University, Hda. San José s/n y Proyecto Yachay, Urcuquí 100119, Ecuador.
Nelson Santiago VispoSchool of Biological Sciences & Engineering, Yachay Tech University, Hda. San José s/n y Proyecto Yachay, Urcuquí 100119, Ecuador.ORCID 0000-0002-4081-3984
Jenny RodriguezEscuela Superior Politécnica del Litoral (ESPOL), Centro Nacional de Acuicultura e Investigaciones Marinas (CENAIM), Campus Gustavo Galindo Km 30.5 Vía Perimetral, Guayaquil 090211, Ecuador.ORCID 0000-0002-4773-0700
Marco Esteban Gudiño-GomezjuradoSchool of Biological Sciences & Engineering, Yachay Tech University, Hda. San José s/n y Proyecto Yachay, Urcuquí 100119, Ecuador.ORCID 0000-0002-8609-0806
Fernando AlbericioSchool of Chemistry and Physics, University of KwaZulu-Natal, Durban 4001, South Africa.ORCID 0000-0002-8946-0462
Markus P TellkampSchool of Biological Sciences & Engineering, Yachay Tech University, Hda. San José s/n y Proyecto Yachay, Urcuquí 100119, Ecuador.
Frank AlexisPolitecnico, Universidad San Francisco de Quito USFQ, Quito 170901, Ecuador.ORCID 0000-0002-0597-7940

Funding

National Research Foundation Blue SkiesYachay TEch Institutional Grant
6 · The paper itself

Abstract

Peptide therapeutics play a key role in the development of new medical treatments. The traditional focus on endogenous peptides has shifted from first discovering other natural sources of these molecules, to later synthesizing those with unique bioactivities. This review provides concise information concerning antimicrobial peptides derived from marine crustaceans for the development of new therapeutics. Marine arthropods do not have an adaptive immune system, and therefore, they depend on the innate immune system to eliminate pathogens. In this context, antimicrobial peptides (AMPs) with unique characteristics are a pivotal part of the defense systems of these organisms. This review covers topics such as the diversity and distribution of peptides in marine arthropods (crustacea and chelicerata), with a focus on penaeid shrimps. The following aspects are covered: the defense system; classes of AMPs; molecular characteristics of AMPs; AMP synthesis; the role of penaeidins, anti-lipopolysaccharide factors, crustins, and stylicins against microorganisms; and the use of AMPs as therapeutic drugs. This review seeks to provide a useful compilation of the most recent information regarding AMPs from marine crustaceans, and describes the future potential applications of these molecules.

Indexed as

ArthropodsPenaeidaeAmino Acid SequenceAnimalsAntimicrobial Cationic PeptidesAntimicrobial PeptidesAntimicrobial Cationic PeptidesAntimicrobial PeptidesAMPantimicrobial peptidescrustaceansdefense systemdrugshrimp

Identifiers

PMID36005504
PMCPMC9409781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.