Evidence map›Paper›PMID 36005386›Full record

ArticleInternational forum of allergy & rhinology2023

Genetics of denatonium-responsive bitter receptors in aspirin-exacerbated respiratory disease.

Jennifer E Douglas, Cailu Lin, Corrine J Mansfield, Katherine Bell, Mandy K Salmon, Michael A Kohanski, Nithin D Adappa, James N Palmer, John V Bosso, Danielle R Reed and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer E DouglasDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Cailu LinMonell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Corrine J MansfieldMonell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Katherine BellMonell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Mandy K SalmonDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Michael A KohanskiDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Nithin D AdappaDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
James N PalmerDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
John V BossoDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
Danielle R ReedMonell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Noam A CohenDepartment of Otorhinolaryngology-Head & Neck Surgery, Perelman School of Medicine, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Funding

Molecular BiologyP30DC011735 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI MARGOLSKEE, ROBERT F. · 2011 to 2015
$2.5M
Immune function of bitter taste receptors in human macrophagesR01AI167971 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Nithin Adappa, Robert J. Lee · 2022 to 2026
$2.5M
Chronic Rhinosinusitis and genetics of bitter taste receptorsR01DC013588 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI COHEN, NOAM A · 2014 to 2018
$2.4M
Taste Receptor Genetics, The Sinonasal Microbiome and Chronic RhinosinusitisI01CX001617 · VA · PHILADELPHIA VA MEDICAL CENTER · PI COHEN, NOAM A · 2018 to 2022
–
CSRD VA I01 CX001617NIAID NIH HHS R01 AI167971NIDCD NIH HHS P30 DC011735NIDCD NIH HHS R01 DC013588
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quaternary Ammonium CompoundsTasteAspirinDysgeusiaHumansReceptors, G-Protein-CoupledAspirindenatoniumQuaternary Ammonium CompoundsReceptors, G-Protein-Coupledaspirin-exacerbated respiratory diseasebitterchronic rhinosinusitisgeneopen arraysensorytaste

Identifiers

PMID36005386
PMCPMC9957822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.