Evidence map›Paper›PMID 36005291›Full record

ArticleeLife2022

In situ single particle classification reveals distinct 60S maturation intermediates in cells.

Bronwyn A Lucas, Kexin Zhang, Sarah Loerch, Nikolaus Grigorieff

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Structural basis for non-AUG translation regulation by 5MPs.bioRxiv : the preprint server for biology · 2025
    Article
  6. Cryo-EM single-particle analysis expanding towards increasingly native samples.Acta crystallographica. Section D, Structural biology · 2025
    Review
  7. Article
  8. Article
  9. Emergent microenvironments of nucleoli.Nucleus (Austin, Tex.) · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Quantification of gallium cryo-FIB milling damage in biological lamellae.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Review
  18. PreparingFrontiers in plant science · 2023
    Article
  19. Recent advances and current trends in cryo-electron microscopy.Current opinion in structural biology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bronwyn A LucasRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID 0000-0001-9162-0421
Kexin ZhangRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.
Sarah LoerchHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, United States.ORCID 0000-0002-1731-516X
Nikolaus GrigorieffRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.ORCID 0000-0002-1506-909X

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Previously, we showed that high-resolution template matching can localize ribosomes in two-dimensional electron cryo-microscopy (cryo-EM) images of untilted

Indexed as

Saccharomyces cerevisiae ProteinsCryoelectron MicroscopyLikelihood FunctionsModels, MolecularRibosomesSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteins2DTMcell biologyFIB-millingin situ cryo-EMmolecular biophysicsnucleusparticle classificationribosome biogenesisS. cerevisiaestructural biology

Identifiers

PMID36005291
PMCPMC9444246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.