Evidence map›Paper›PMID 36005202›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Functional and Survival Outcomes of Patients following the Harrington Procedure for Complex Acetabular Metastatic Lesions.

Andrea Plaud, Jean Gaillard, François Gouin, Aurélie Le Thuaut, Peggy Ageneau, Juliane Berchoud, Alban Fouasson-Chailloux, Vincent Crenn

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Andrea PlaudClinique Chirurgicale Orthopédique et Traumatologique, Nantes Université, CHU Nantes, 1 Place Alexis Ricordeau, 44000 Nantes, France.
Jean GaillardClinique Chirurgicale Orthopédique et Traumatologique, Nantes Université, CHU Nantes, 1 Place Alexis Ricordeau, 44000 Nantes, France.
François GouinDépartement de Chirurgie, Centre de Lutte Contre le Cancer Léon Bérard, 69008 Lyon, France.
Aurélie Le ThuautPlateforme de Méthodologie et Biostatistique, Direction de la Recherche et de l'Innovation, Nantes Université, CHU Nantes, 44000 Nantes, France.ORCID 0000-0002-4780-5637
Peggy AgeneauClinique Chirurgicale Orthopédique et Traumatologique, Nantes Université, CHU Nantes, 1 Place Alexis Ricordeau, 44000 Nantes, France.
Juliane BerchoudClinique Chirurgicale Orthopédique et Traumatologique, Nantes Université, CHU Nantes, 1 Place Alexis Ricordeau, 44000 Nantes, France.
Alban Fouasson-ChaillouxMédecine Physique et Réadaptation Locomotrice, Nantes Université, CHU Nantes, 85 rue Saint Jacques, 44093 Nantes, France.ORCID 0000-0002-8139-814X
Vincent CrennClinique Chirurgicale Orthopédique et Traumatologique, Nantes Université, CHU Nantes, 1 Place Alexis Ricordeau, 44000 Nantes, France.ORCID 0000-0002-6563-8895
Centre Hospitalier Universitaire de Nantes · FRCentre Léon Bérard · FRCentre National de la Recherche Scientifique · FRInserm · FRNantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Harrington surgical technique makes it possible to manage complex, extensive bone lesions using pins and cement to consolidate bone for acetabular cup positioning. However, it may be associated with a high reoperation rate, and the functional results of this surgery are not precisely described in the literature.

methodsIn a monocentric retrospective study including all patients operated on using the Harrington procedure associated with THA between 2005 and 2020, we aimed to assess preoperative and postoperative function, reoperation-free survival, and overall survival.

resultsFunctional improvement was significant for Parker scores (preoperative: 3.6 ± 2.0; 6-month follow-up: 6.6 ± 3.2; 12-month follow-up: 7.6 ± 2.1) and Musculoskeletal Tumor Society (MSTS) scores (preoperative: 31.1 ± 16.2%; 6-month follow-up: 67.7 ± 30.6%; 12-month follow-up: 82.4 ± 24.0%). Of the 21 patients included, the reoperation-free survival rate was 76.1% [CI 95%: 58.1-99.7] at six and twelve months, with the main complications being pin migration (50.0%) and infection (25%). The patient overall survival rate was 76.2% [95% CI: 59.9-96.7] at six months and 61.9% [95% CI: 59.9-96.7] at 12 months. DISCUSSION: These results underlined significant functional improvements following a conventional Harrington procedure, with acceptable reoperation rates.

Indexed as

Arthroplasty, Replacement, HipBone NeoplasmsAcetabulumHumansRetrospective Studiesacetabular lesionbone metastasisfunctional assessmentHarrington procedure

Identifiers

PMID36005202
PMCPMC9406529
OpenAlexW4293103970

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.