Evidence map›Paper›PMID 36005165›Full record

ReviewCurrent oncology (Toronto, Ont.)2022

Exosomal Non-Coding RNAs: New Insights into the Biology of Hepatocellular Carcinoma.

Qian Zhang, Hanlin Li, Yang Liu, Jian Li, Chunling Wu, Hua Tang

Open access · goldAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Current trends in exosomes as therapeutic drug delivery systems.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
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  5. DeepBBMC biology · 2025
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  16. Computational identification of promoters inFrontiers in microbiology · 2023
    Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qian ZhangSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.
Hanlin LiSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0002-5853-8618
Yang LiuSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.
Jian LiSchool of Basic Medical Sciences, Chengdu University, Chengdu 610106, China.
Chunling WuSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.
Hua TangSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0001-6728-4544
Southwest Medical University · CNChengdu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest extracellular vesicles released by cells. They deliver different cargoes, including proteins, DNAs, and RNAs, and facilitate communication between cells to coordinate a variety of physiological and pathological functions. Hepatocellular carcinoma (HCC) is the sixth common malignant tumor and the fourth leading cause of cancer-related death worldwide. Its molecular mechanism remains largely unknown, and there is a lack of reliable and noninvasive biomarkers for early diagnosis and prognosis prediction. Mounting evidence has shown that exosomes carry a variety of ncRNAs, such as long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNAs), which play critical roles in the occurrence and progression of HCC. In this review, we summarize the recent findings of exosomal miRNAs, lncRNAs, and circRNAs in HCC from their impact on the development of HCC to their potential applications in the diagnosis and treatment of HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsRNA, Long NoncodingBiologyHumansRNA, CircularMicroRNAsRNA, CircularRNA, Long Noncodingexosomehepatocellular carcinomalong non-coding RNAmicroRNAtumor microenvironment

Identifiers

PMID36005165
PMCPMC9406833
OpenAlexW4289111352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.