Evidence map›Paper›PMID 36005161›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Treatment of Basal Cell Carcinoma with Electrochemotherapy: Insights from the InspECT Registry (2008-2019).

Giulia Bertino, Tobian Muir, Joy Odili, Ales Groselj, Roberto Marconato, Pietro Curatolo, Erika Kis, Camilla Kjaer Lonkvist, James Clover, Pietro Quaglino and 6 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. S2k guideline basal cell carcinoma of the skin (update 2023).Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 7 countries.

Giulia BertinoDepartment of Otolaryngology-Head and Neck Surgery, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Tobian MuirSouth Tees NHS Foundation Trust, Middlesbrough TS4 3BW, UK.
Joy OdiliDepartment of Plastic Surgery, St. George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK.
Ales GroseljDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Zaloska 2, 1000 Ljubljana, Slovenia.
Roberto MarconatoSchool of Surgery, University of Padova, 27100 Padova, Italy.
Pietro CuratoloDermatology Unit, Department of Internal Medicine and Medical Specialties, University "La Sapienza", 00042 Rome, Italy.
Erika KisDepartment of Dermatology and Allergology, Albert Szent-Györgyi Clinical Centre, University of Szeged, 6700 Szeged, Hungary.ORCID 0000-0002-8305-7656
Camilla Kjaer LonkvistDepartment of Oncology, Herlev and Gentofte Hospital, University of Copenhagen, 2730 Herlev, Denmark.
James CloverCork Cancer Research Centre, University College Cork, T12 YN60 Cork, Ireland.
Pietro QuaglinoDepartment of Medical Sciences, Dermatologic Clinic, University of Turin, 10094 Turin, Italy.
Christian KunteDepartment of Dermatologic Surgery and Dermatology, Artemed Fachklinik München, 81379 Munich, Germany.
Romina SpinaPsychology Unit, University Hospital of Padova, 35100 Padova, Italy.
Veronica SecciaOtolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy.
Francesca de TerlizziIGEA Clinical Biophysics Department, Via Parmenide 10/A, Carpi, 41012 Modena, Italy.ORCID 0000-0002-2676-4549
Luca Giovanni CampanaDepartment of Surgery, Manchester University NHS Foundation Trust, Manchester Royal Infirmary, Oxford Rd, Manchester M13 9WL, UK.
The InspECT Bcc Working Group
University of Padua · ITAzienda Ospedaliera Universitaria Pisana · ITIGEA Clinical Biophysics (Italy) · ITLjubljana University Medical Centre · SIManchester Royal Infirmary · GBMünchen Klinik · DEPoliclinico San Matteo Fondazione · ITSapienza University of Rome · ITSouth Tees Hospitals NHS Foundation Trust · GBSt George’s University Hospitals NHS Foundation Trust · GBUniversity College Cork · IEUniversity of Copenhagen · DKUniversity of Szeged · HUUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective registry-based study aims to describe electrochemotherapy (ECT) modalities in basal cell carcinoma (BCC) patients and evaluate its efficacy, safety, and predictive factors. The International Network for Sharing Practices of Electrochemotherapy (InspECT) multicentre database was queried for BCC cases treated with bleomycin-ECT between 2008 and 2019 (n = 330 patients from seven countries, with 623 BCCs [median number: 1/patient; range: 1-7; size: 13 mm, range: 5-350; 85% were primary, and 80% located in the head and neck]). The procedure was carried out under local anaesthesia in 68% of cases, with the adjunct of mild sedation in the remaining 32%. Of 300 evaluable patients, 242 (81%) achieved a complete response (CR) after a single ECT course. Treatment naïvety (odds ratio [OR] 0.35, 95% confidence interval [C.I.] 0.19-0.67,

Indexed as

Basal Cell CarcinomaElectrochemotherapySkin NeoplasmsBleomycinHumansRegistriesBleomycinbasal cell carcinomableomycinelectrochemotherapyelectroporationskin cancer

Identifiers

PMID36005161
PMCPMC9406883
OpenAlexW4288445121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.