Evidence map›Paper›PMID 36005112›Full record

ReviewGels (Basel, Switzerland)2022

Glaucoma Treatment and Hydrogel: Current Insights and State of the Art.

Antonio Maria Fea, Cristina Novarese, Paolo Caselgrandi, Giacomo Boscia

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Antonio Maria FeaDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, Italy.
Cristina NovareseDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, Italy.ORCID 0000-0002-4120-5489
Paolo CaselgrandiDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, Italy.ORCID 0000-0002-7153-1074
Giacomo BosciaDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the treatment of several eye diseases. Their chemical structure enables them to incorporate various ophthalmic medications, achieving their optimal therapeutic doses and providing more clinically relevant time courses (weeks or months as opposed to hours and days), which will inevitably reduce dose frequency, thereby improving patient compliance and clinical outcomes. Due to its chronic course, the treatment of glaucoma may benefit from applying gel technologies as drug-delivering systems and as antifibrotic treatment during and after surgery. Therefore, our purpose is to review current applications of ophthalmic gelling systems with particular emphasis on glaucoma.

Indexed as

drug deliveryglaucomaglaucoma therapyglaucoma treatmenthydrogelhydrogel in glaucomahydrogel in ophthalmologynanoparticlesophthalmology

Identifiers

PMID36005112
PMCPMC9407420
OpenAlexW4292261936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.