Evidence map›Paper›PMID 36005092›Full record

ArticleGels (Basel, Switzerland)2022

Dextrin-Based Nanohydrogels for Rokitamycin Prolonged Topical Delivery.

Maria Tannous, Silvia Lucia Appleton, Gjylije Hoti, Fabrizio Caldera, Monica Argenziano, Yousef Khazaei Monfared, Adrián Matencio, Francesco Trotta, Roberta Cavalli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria TannousDipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.ORCID 0000-0001-9281-0710
Silvia Lucia AppletonDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.
Gjylije HotiDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0002-0541-980X
Fabrizio CalderaDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0003-2581-0555
Monica ArgenzianoDipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.ORCID 0000-0002-8485-7460
Yousef Khazaei MonfaredDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0002-1171-8670
Adrián MatencioDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0001-8203-0673
Francesco TrottaDipartimento di Chimica, Università di Torino, Via P. Giuria 7, 10125 Torino, Italy.
Roberta CavalliDipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via P. Giuria 9, 10125 Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrolides are widely used antibiotics with a broad spectrum of activity. The development of drug carriers to deliver this type of antibiotics has attracted much research. The present study aims at developing new swellable dextrin-based nanohydrogels for the topical delivery of rokitamycin, as model macrolide. Rokitamycin is a synthetic analogous of macrolides with advantageous characteristics as far as bacterial uptake and post-antibiotic effect are concerned. It is also indicated for the treatment of severe infections caused by

Indexed as

cyclodextrinformulationlinecapsnanohydrogelsnanospongesrokitamycin

Identifiers

PMID36005092
PMCPMC9407297
OpenAlexW4293104078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.