Evidence map›Paper›PMID 36005045›Full record

ArticleBiosensors2022

Electrochemical DNA Biosensor Based on Mercaptopropionic Acid-Capped ZnS Quantum Dots for Determination of the Gender of Arowana Fish.

Eka Safitri, Lee Yook Heng, Musa Ahmad, Ling Ling Tan, Nazaruddin Nazaruddin, Khairi Suhud, Chew Poh Chiang, Muhammad Iqhrammullah

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eka SafitriDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Darussalam, Banda Aceh 23111, Indonesia.ORCID 0000-0002-8023-3095
Lee Yook HengDepartment of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor Darul Ehsan, Malaysia.
Musa AhmadChemical Technology Program, Faculty of Science and Technology, University Sains Islam Malaysia (USIM), Nilai 91800, Negeri Sembilan, Malaysia.
Ling Ling TanSoutheast Asia Disaster Prevention Research Initiative (SEADPRI-UKM), Institute for Environment and Development (LESTARI), Universiti Kebangsaan Malaysia, Bangi 43600, Selangor Darul Ehsan, Malaysia.ORCID 0000-0001-9978-5140
Nazaruddin NazaruddinDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Darussalam, Banda Aceh 23111, Indonesia.
Khairi SuhudDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Darussalam, Banda Aceh 23111, Indonesia.
Chew Poh ChiangFreshwater Fisheries Research Division, Fisheries Research Institute Glami Lemi, Jelebu 71650, Negeri Sembilan, Malaysia.ORCID 0000-0002-6722-264X
Muhammad IqhrammullahDepartment of Life Sciences and Chemistry, Jacobs University Bremen, 28759 Bremen, Germany.ORCID 0000-0001-8060-7088

Funding

Universiti Kebangsaan Malaysia and Department of Fishery, Malaysia XX-2014-005
6 · The paper itself

Abstract

A new electrochemical DNA biosensor based on mercaptopropionic acid (MPA)-capped ZnS quantum dots (MPA-ZnS QDs) immobilization matrix for covalent binding with 20-base aminated oligonucleotide has been successfully developed. Prior to the modification, screen-printed carbon paste electrode (SPE) was self-assembled with multilayer gold nanoparticles (AuNPs) and cysteamine (Cys). The inclusion of MPA-ZnS QDs semiconducting material in modified electrodes has enhanced the electron transfer between the SPE transducer and DNA leading to improved bioanalytical assay of target biomolecules. Electrochemical studies performed by cyclic voltammetry (CV) and differential pulsed voltammetry (DPV) demonstrated that the MPA-ZnS QDs modified AuNPs electrode was able to produce a lower charge transfer resistance response and hence higher electrical current response. Under optimal conditions, the immobilized synthetic DNA probe exhibited high selectivity towards synthetic target DNA. Based on the DPV response of the reduction of anthraquinone monosulphonic acid (AQMS) redox probe, the MPA-ZnS QDs-based electrochemical DNA biosensor responded to target DNA concentration from 1 × 10

Indexed as

Biosensing TechniquesMetal NanoparticlesQuantum DotsAnimalsDNADNA ProbesElectrochemical TechniquesElectrodesGoldPolymersPyrrolesReproducibility of ResultsSulfidesZinc CompoundsDNADNA ProbesGoldPolymersPyrrolesSulfidesZinc Compoundszinc sulfideDNA biosensorelectrochemistrygold nanoparticlesscreen printed electrodeZnS QDs

Identifiers

PMID36005045
PMCPMC9405751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.