Evidence map›Paper›PMID 36005018›Full record

ArticleBiosensors2022

Electrochemical Biosensor for SARS-CoV-2 cDNA Detection Using AuPs-Modified 3D-Printed Graphene Electrodes.

Luiz R G Silva, Jéssica S Stefano, Luiz O Orzari, Laís C Brazaca, Emanuel Carrilho, Luiz H Marcolino-Junior, Marcio F Bergamini, Rodrigo A A Munoz, Bruno C Janegitz

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  4. Advanced electrochemical biosensing exploiting mussel-inspired polydopamine interfaces.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Luiz R G SilvaDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, Araras 13600-970, SP, Brazil.
Jéssica S StefanoDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, Araras 13600-970, SP, Brazil.ORCID 0000-0002-2838-3555
Luiz O OrzariDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, Araras 13600-970, SP, Brazil.
Laís C BrazacaSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos 13566-590, SP, Brazil.ORCID 0000-0002-0456-7552
Emanuel CarrilhoSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos 13566-590, SP, Brazil.ORCID 0000-0001-7351-8220
Luiz H Marcolino-JuniorChemistry Department, Laboratory of Electrochemical Sensors (LabSensE), Federal University of Paraná, Curitiba 81531-980, PR, Brazil.
Marcio F BergaminiChemistry Department, Laboratory of Electrochemical Sensors (LabSensE), Federal University of Paraná, Curitiba 81531-980, PR, Brazil.ORCID 0000-0002-4600-2250
Rodrigo A A MunozNational Institute of Science and Technology in Bioanalysis-INCTBio, Campinas 13083-970, SP, Brazil.ORCID 0000-0001-8230-5825
Bruno C JanegitzDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, Araras 13600-970, SP, Brazil.ORCID 0000-0001-9707-9795
Universidade Federal de São Carlos · BRUniversidade Federal do Paraná · BRBrazilian Biosciences National Laboratory · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.510506/2020-00Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.510880/2020-00National Council for Scientific and Technological Development 303338/2019-9National Council for Scientific and Technological Development 307271/2017-0National Council for Scientific and Technological Development 427731/2018-6National Council for Scientific and Technological Development 465389/2014-7São Paulo Research Foundation 2017/21097-3São Paulo Research Foundation 2018/19750-3São Paulo Research Foundation 2022/06145-0
6 · The paper itself

Abstract

A low-cost and disposable graphene polylactic (G-PLA) 3D-printed electrode modified with gold particles (AuPs) was explored to detect the cDNA of SARS-CoV-2 and creatinine, a potential biomarker for COVID-19. For that, a simple, non-enzymatic electrochemical sensor, based on a Au-modified G-PLA platform was applied. The AuPs deposited on the electrode were involved in a complexation reaction with creatinine, resulting in a decrease in the analytical response, and thus providing a fast and simple electroanalytical device. Physicochemical characterizations were performed by SEM, EIS, FTIR, and cyclic voltammetry. Square wave voltammetry was employed for the creatinine detection, and the sensor presented a linear response with a detection limit of 0.016 mmol L

Indexed as

Biosensing TechniquesCOVID-19GraphiteCreatinineDNA, ComplementaryElectrochemical TechniquesElectrodesHumansPolyestersPrinting, Three-DimensionalSARS-CoV-2CreatinineDNA, ComplementaryGraphitePolyesters3D printed electrodeAuP modified electrodecreatinineelectrochemical (bio)sensorSARS-CoV-2

Identifiers

PMID36005018
PMCPMC9405530
OpenAlexW4292291435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.