Evidence map›Paper›PMID 36004989›Full record

ArticleBiosensors2022

Determination of rSpike Protein by Specific Antibodies with Screen-Printed Carbon Electrode Modified by Electrodeposited Gold Nanostructures.

Maryia Drobysh, Viktorija Liustrovaite, Ausra Baradoke, Roman Viter, Chien-Fu Chen, Arunas Ramanavicius, Almira Ramanaviciene

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 45 citations in OpenAlex.

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  4. MoSMicromachines · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Maryia DrobyshState Research Institute Center for Physical and Technological Sciences, Sauletekio Ave. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0003-1257-0396
Viktorija LiustrovaiteNanoTechnas-Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.
Ausra BaradokeState Research Institute Center for Physical and Technological Sciences, Sauletekio Ave. 3, LT-10257 Vilnius, Lithuania.
Roman ViterInstitute of Atomic Physics and Spectroscopy, University of Latvia, Jelgavas Street 3, LV-1004 Riga, Latvia.
Chien-Fu ChenInstitute of Applied Mechanics, National Taiwan University, 1 Sec. 4, Roosevelt Rd., Da'an Dist., Taipei City 106, Taiwan.
Arunas RamanaviciusState Research Institute Center for Physical and Technological Sciences, Sauletekio Ave. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Almira RamanavicieneNanoTechnas-Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0001-5864-0359
Vilnius University · LTCenter for Physical Sciences and Technology · LTNational Taiwan University · TWSumy State University · UA

Funding

Lietuvos Mokslo Taryba S-LLT-21-3
6 · The paper itself

Abstract

In this research, we assessed the applicability of electrochemical sensing techniques for detecting specific antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins in the blood serum of patient samples following coronavirus disease 2019 (COVID-19). Herein, screen-printed carbon electrodes (SPCE) with electrodeposited gold nanostructures (AuNS) were modified with L-Cysteine for further covalent immobilization of recombinant SARS-CoV-2 spike proteins (rSpike). The affinity interactions of the rSpike protein with specific antibodies against this protein (anti-rSpike) were assessed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. It was revealed that the SPCE electroactive surface area increased from 1.49 ± 0.02 cm

Indexed as

Biosensing TechniquesCOVID-19NanostructuresAntibodiesCarbonElectrochemical TechniquesElectrodesGoldHumansImmunoassayLimit of DetectionSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodiesCarbonGoldSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antigen–antibody complexCOVID-19cyclic voltammetry (CV)differential pulse voltammetry (DPV)electrochemical immunosensorelectrochemical impedance spectroscopy (EIS)gold nanostructures (AuNS)SARS-CoV-2 virusself-assembled monolayer (SAM)spike protein (Spike)

Identifiers

PMID36004989
PMCPMC9405582
OpenAlexW4289704747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.