Evidence map›Paper›PMID 36004971›Full record

ReviewBiosensors2022

Cost-Effective Fiber Optic Solutions for Biosensing.

Cátia Leitão, Sónia O Pereira, Carlos Marques, Nunzio Cennamo, Luigi Zeni, Madina Shaimerdenova, Takhmina Ayupova, Daniele Tosi

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cátia Leitãoi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-6331-1215
Sónia O Pereirai3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4174-7253
Carlos Marquesi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-8596-5092
Nunzio CennamoDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy.ORCID 0000-0001-7769-0984
Luigi ZeniDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy.ORCID 0000-0001-8356-7480
Madina ShaimerdenovaSchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.
Takhmina AyupovaSchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0001-9906-372X
Daniele TosiSchool of Engineering and Digital Sciences, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0002-6500-4964

Funding

FDA HHS R01 FD003908
6 · The paper itself

Abstract

In the last years, optical fiber sensors have proven to be a reliable and versatile biosensing tool. Optical fiber biosensors (OFBs) are analytical devices that use optical fibers as transducers, with the advantages of being easily coated and biofunctionalized, allowing the monitorization of all functionalization and detection in real-time, as well as being small in size and geometrically flexible, thus allowing device miniaturization and portability for point-of-care (POC) testing. Knowing the potential of such biosensing tools, this paper reviews the reported OFBs which are, at the moment, the most cost-effective. Different fiber configurations are highlighted, namely, end-face reflected, unclad, D- and U-shaped, tips, ball resonators, tapered, light-diffusing, and specialty fibers. Packaging techniques to enhance OFBs' application in the medical field, namely for implementing in subcutaneous, percutaneous, and endoscopic operations as well as in wearable structures, are presented and discussed. Interrogation approaches of OFBs using smartphones' hardware are a great way to obtain cost-effective sensing approaches. In this review paper, different architectures of such interrogation methods and their respective applications are presented. Finally, the application of OFBs in monitoring three crucial fields of human life and wellbeing are reported: detection of cancer biomarkers, detection of cardiovascular biomarkers, and environmental monitoring.

Indexed as

Biosensing TechniquesFiber Optic TechnologyCost-Benefit AnalysisHumansOptical FibersSmartphonecancer biomarkerscardiovascular biomarkersenvironmental monitoringoptical interrogation methodsPOC monitoringsmartphone optical biosensors

Identifiers

PMID36004971
PMCPMC9405647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.