ArticleBlood2022
Premature aging of the immune system affects the response to SARS-CoV-2 mRNA vaccine in β-thalassemia: role of an additional dose.
Open access · greenAbstract read
In one paragraph
Article in Blood, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Effects of Sirolimus treatment on patients with β-Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4Journal of cellular and molecular medicine · 2023Trial
- Underlying disease is the main risk factor in post-splenectomy complication risk: Data from a national database.British journal of haematology · 2025Article
- Impairment of Innate Immunity and Depletion of Vaccine-Induced Memory B and T Cells in the Absence of the Spleen.American journal of hematology · 2025Article
- T and B cell responses in different immunization scenarios for COVID-19: a narrative review.Frontiers in immunology · 2025Review
- Absence of blood donors' anti-SARS-CoV-2 antibodies in pre-storage leukoreduced red blood cell units indicates no role of passive immunity for blood recipients.Annals of hematology · 2024Article
- Clinical outcome and humoral immune responses of β-thalassemia major patients with severe iron overload to SARS-CoV-2 infection and vaccination: a prospective cohort study.EClinicalMedicine · 2023Article
- Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study.Hematology reports · 2023Article
- Article
- Epidemiological Surveillance of SARSCov2 in β-Thalassemia Patients in the Last Two Years: Reinfection Rate, Insights and Future Challenges.Mediterranean journal of hematology and infectious diseases · 2023Article
- Emerging viral infections in immunocompromised patients: A great challenge to better define the role of immune response.Frontiers in immunology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 10 institutions in 1 country.
Rita CarsettiB-Cell Laboratory, Immunology Research Area, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Bambino Gesù Children's Hospital, Rome, Italy.ORCID 0000-0002-2632-1078
Chiara AgratiLaboratory of Cellular Immunology, IRCCS, INMI L. Spallanzani, Rome, Italy.
Valeria Maria PintoCenter for Microcythemia, Congenital Anemia, and Iron Dysmetabolism, Galliera Hospital, Genoa, Italy.ORCID 0000-0002-8375-6289
Barbara GianesinCenter for Microcythemia, Congenital Anemia, and Iron Dysmetabolism, Galliera Hospital, Genoa, Italy.
Rita GamberiniDay Hospital della Talassemia e delle Emoglobinopatie, Dipartimento di Medicina, Azienda Ospedaliero-Universitaria S. Anna, Cona di Ferrara, Ferrara, Italy.
Monica FortiniDay Hospital della Talassemia e delle Emoglobinopatie, Dipartimento di Medicina, Azienda Ospedaliero-Universitaria S. Anna, Cona di Ferrara, Ferrara, Italy.ORCID 0000-0001-8406-0024
Susanna BarellaSSD Talassemia, Ospedale Pediatrico Microcitemico "A. Cao", ASL8, Cagliari, Italy.
Rita DenottiSSD Talassemia, Ospedale Pediatrico Microcitemico "A. Cao", ASL8, Cagliari, Italy.
Silverio PerrottaDipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università, degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.ORCID 0000-0001-6149-6845
Maddalena CasaleDipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università, degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Aurelio MaggioCampus of Hematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo, Italy.
Lorella PitroloCampus of Hematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo, Italy.
Eleonora TartagliaLaboratory of Cellular Immunology, IRCCS, INMI L. Spallanzani, Rome, Italy.ORCID 0000-0001-5773-7781
Eva Piano MortariB-Cell Laboratory, Immunology Research Area, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Bambino Gesù Children's Hospital, Rome, Italy.ORCID 0000-0002-0054-4732
Francesca ColavitaLaboratory of Virology, IRCCS, INMI L. Spallanzani, IRCCS, Rome, Italy.
Vincenzo PuroRisk Management and Biosafety Unit, IRCCS, INMI L Spallanzani, Rome, Italy.
Massimo FrancalanciaLaboratory of Virology, IRCCS, INMI L. Spallanzani, IRCCS, Rome, Italy.ORCID 0000-0003-3133-9237
Valeria MariniClinical Pharmacology Unit, EO Ospedali Galliera, Genoa, Italy.
Marco CaminatiDepartment of Medicine, University of Verona & AOUI Verona, Policlinico GB Rossi, Verona, Italy.ORCID 0000-0001-7383-1487
Filippo MazziDepartment of Medicine, University of Verona & AOUI Verona, Policlinico GB Rossi, Verona, Italy.
Lucia De FranceschiDepartment of Medicine, University of Verona & AOUI Verona, Policlinico GB Rossi, Verona, Italy.ORCID 0000-0001-7093-777X
Gian Luca ForniCenter for Microcythemia, Congenital Anemia, and Iron Dysmetabolism, Galliera Hospital, Genoa, Italy.ORCID 0000-0001-9833-1016
Franco LocatelliDepartment of Pediatric Hematology and Oncology, IRCCS Bambino Gesù Children's Hospital, Catholic University of the Sacred Heart, Rome, Italy.
Ente Ospedaliero Ospedali Galliera · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Verona · ITArcispedale Sant'Anna · ITBambino Gesù Children's Hospital · ITOspedale Microcitemico · ITOspedale Vincenzo Cervello · ITUniversity of Campania "Luigi Vanvitelli" · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITUniversità Cattolica del Sacro Cuore · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Aging, Prematurebeta-ThalassemiaCOVID-19Antibodies, ViralCOVID-19 VaccinesHumansImmune SystemmRNA VaccinesSARS-CoV-2Vaccines, SyntheticAntibodies, ViralCOVID-19 VaccinesmRNA VaccinesVaccines, Synthetic
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.