Evidence map›Paper›PMID 36004365›Full record

ArticleAccess microbiology2022

Genetic diversity and antimicrobial resistance of invasive, noninvasive and colonizing group B

Otto Henrique May Feuerschuette, Eduardo Venâncio Alves, Mara Cristina Scheffer, Ana Paula Pessoa Vilela, Fernando Hartmann Barazzetti, Henrique Miranda Feuerschuette, Ana Carolina Lobor Cancelier, Maria Luiza Bazzo

Abstract read
In one paragraph

Article in Access microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A Comparative Analysis of Molecular Epidemiology and Antibiotic Resistance in Group B Streptococcus Isolated From Invasive and Noninvasive Adult Cases in Daejeon, South Korea.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Otto Henrique May FeuerschuetteHospital Universitário Professor Polydoro Ernani de São Thiago, HU/UFSC, Florianópolis, Brazil.ORCID https://orcid.org/0000-0002-7561-4790
Eduardo Venâncio AlvesLaboratório de Biologia Molecular, Microbiologia e Sorologias, HU/UFSC, Florianópolis, Brazil.
Mara Cristina SchefferHospital Universitário Professor Polydoro Ernani de São Thiago, HU/UFSC, Florianópolis, Brazil.ORCID https://orcid.org/0000-0003-2735-5197
Ana Paula Pessoa VilelaLaboratório de Biologia Molecular, Microbiologia e Sorologias, HU/UFSC, Florianópolis, Brazil.ORCID https://orcid.org/0000-0001-9030-0688
Fernando Hartmann BarazzettiLaboratório de Biologia Molecular, Microbiologia e Sorologias, HU/UFSC, Florianópolis, Brazil.
Henrique Miranda FeuerschuetteUniversidade do Sul de Santa Catarina - UNISUL, Tubarão, Brazil.
Ana Carolina Lobor CancelierUniversidade do Sul de Santa Catarina - UNISUL, Tubarão, Brazil.
Maria Luiza BazzoLaboratório de Biologia Molecular, Microbiologia e Sorologias, HU/UFSC, Florianópolis, Brazil.ORCID https://orcid.org/0000-0003-1292-0974

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Group B Gap Statement: The authors hypothesize that knowledge of regional GBS genetic patterns may allow the use of prevention and treatment measures to reduce the burden of streptococcal disease. Aim: The aim was to report the genotypic diversity and antimicrobial sensitivity profiles of invasive, noninvasive urinary and colonizing GBS strains, and evaluate the relationships between these findings. Methodology: The study included consecutive and non-duplicated GBS isolates recovered in southern Brazil from 2015 to 2017. We performed multiple-locus variable-number tandem repeat analysis (MLVA) and PCR analyses to determine capsular serotypes and identify the presence of the resistance genes Results: The sample consisted of 348 GBS strains, 42 MLVA types were identified, and 4 of them represented 64 % of isolates. Serotype Ia was the most prevalent (42.2 %) and was found in a higher percentage associated with colonization, followed by serotypes V (24.4 %), II (17.8 %) and III (7.8 %). Serotype V was associated with invasive isolates and serotypes II and III with noninvasive isolates, without significant differences. All isolates were susceptible to penicillin. GBS 2018/ Conclusion: This report suggests that the circulating GBS belong to a limited number of genetic lineages. The most common genotypes were Ia/MT12 and V/MT18, which are associated with high resistance to macrolides and the presence of the genes

Indexed as

antimicrobial resistancegenetic diversityGroup B Streptococcus; Streptococcus agalactiaeMLVA

Identifiers

PMID36004365
PMCPMC9394672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.