Evidence map›Paper›PMID 36004221›Full record

ArticleJTCVS open2022

Lobectomy offers improved survival outcomes relative to segmentectomy for >2 but ≤4 cm non-small cell lung cancer tumors.

Terrance Peng, Sean C Wightman, Li Ding, Dustin K Lieu, Scott M Atay, Elizabeth A David, Anthony W Kim

Open access · goldAbstract read
In one paragraph

Article in JTCVS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Segmentectomy for stage IA3 tumours: just another day in clinic.Interdisciplinary cardiovascular and thoracic surgery · 2023
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Terrance PengDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Sean C WightmanDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Li DingDepartment of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, Calif.
Dustin K LieuDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Scott M AtayDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Elizabeth A DavidDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Anthony W KimDivision of Thoracic Surgery, Department of Surgery, Keck School of Medicine of USC, Los Angeles, Calif.
Keck Hospital of USC · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
NCATS NIH HHS UL1 TR001855
6 · The paper itself

Abstract

Objective: The objective was to compare overall survival (OS) between lobectomy and segmentectomy for patients with non-small cell lung cancers (NSCLCs) > 2 but ≤4 cm. Methods: The National Cancer Database was queried to identify treatment-naïve patients with NSCLC tumors >2 but ≤4 cm. Eligible patients were diagnosed with pT1 or T2 N0 M0 disease, underwent lobectomy or segmentectomy, and received no adjuvant therapy. OS was compared using the Kaplan-Meier method, and the Cox proportional-hazards model was used to identify prognostic factors for death. Propensity score matching was performed to minimize the effects of potential confounders. Results: Included were 32,792 patients: lobectomy (n = 31,353) and segmentectomy (n = 1439). Five-year OS was improved following lobectomy over segmentectomy for patients with >2 but ≤4 cm NSCLCs (62.3% vs 52.6%; Conclusions: Lobectomy is associated with superior 5-year OS compared with segmentectomy and may be preferred for NSCLC tumors >2 but ≤4 cm when feasible.

Indexed as

CDCI, Charlson-Deyo comorbidity indexlobectomyNCDB, National Cancer Databasenon–small cell lung cancerNSCLC, non–small cell lung cancerOS, overall survivalPUF, participant user filesegmentectomysublobar resection

Identifiers

PMID36004221
PMCPMC9390142
OpenAlexW4223998492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.