Evidence map›Paper›PMID 36004184›Full record

ArticleJTCVS open2021

Descending necrotizing mediastinitis and the proposal of a new classification.

Kenji Sugio, Tatsuro Okamoto, Yoshimasa Maniwa, Yasushi Toh, Morihito Okada, Taku Yamashita, Shogo Shinohara, Ichiro Yoshino, Masayuki Chida, Hiroyuki Kuwano and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JTCVS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

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  16. The efficacy of thoracoscopic surgery for descending necrotizing mediastinitis.Interdisciplinary cardiovascular and thoracic surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Kenji SugioDepartment of Thoracic and Breast Surgery, Oita University, Oita, Japan.
Tatsuro OkamotoDepartment of Thoracic and Breast Surgery, Oita University, Oita, Japan.
Yoshimasa ManiwaDivision of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Yasushi TohNational Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Morihito OkadaDepartment of Surgical Oncology, Hiroshima University, Hiroshima, Japan.
Taku YamashitaDepartment of Otorhinolaryngology, Head and Neck Surgery, Kitasato University Sagamihara, Kanagawa, Japan.
Shogo ShinoharaDepartment of Otolaryngology, Head and Neck Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.
Ichiro YoshinoDepartment of General Thoracic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Masayuki ChidaDepartment of General Thoracic Surgery, Dokkyo Medical University School of Medicine, Shimotsuga, Japan.
Hiroyuki KuwanoFukuoka City Hospital, Fukuoka, Japan.
Akihiro ShiotaniDepartment of Otolaryngology, National Defense Medical College, Saitama, Japan.
Oita University · JPChiba University · JPDokkyo Medical University · JPFukuoka City Hospital · JPHiroshima University · JPKitasato University · JPKobe City Medical Center General Hospital · JPKobe University · JPNational Defense Medical College · JPNational Hospital Organization Kyushu Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to clarify the clinical features and surgical outcomes of descending necrotizing mediastinitis (DNM) to provide a guide for its surgical treatment, focusing on the type of extension and the deployed procedures. Methods: As a joint study of the Japan Broncho-esophagological Society and the Japanese Association for Chest Surgery (JBES1703/JACS1806 study), the clinical data of consecutive patients with DNM who underwent surgical drainage between 2012 and 2016 were collected from 131 participating institutions. The infection limited to the area superior to the carina level was defined as type I; while spreading to the lower mediastinum (LM) as type II. The LM infection limited to the anterior LM, that spread to both the anterior and posterior LM and that limited the posterior LM (type IIC) were further categorized as type IIA, IIB, and IIC, respectively. Results: A total of 225 patients were ultimately eligible. One hundred patients (44.4%) were categorized as type I, whereas 125 patients were type II (56.6%); The number of type IIA, IIB, and IIC cases was 20 (16%), 62 (49.6%) and 43 (34.4%), respectively. Patients with type I and IIC infections more commonly underwent cervical drainage than patients with type IIA and IIB infections (34.3% and 13.4%, respectively). A total of 8 patients died within 30 days (3.6%, type I/II: 1/7). The 5-year overall survival rate was 68.6%. Type II infection was associated with the 90-day mortality (odds ratio, 5.18; Conclusions: This study demonstrated a previously unclassified group of lower mediastinal extent that is localized within the posterior mediastinum (type IIC). We proposed a new DNM classification including type IIC mediastinitis.

Indexed as

classificationCRF, case report formdescending necrotizing mediastinitisDM, diabetes mellitusDNM, descending necrotizing mediastinitisinfectionJACS, Japanese Association for Chest SurgeryJATS, Japanese Association for Thoracic SurgeryJBES, Japan Broncho-esophagological SocietyLM, lower mediastinummulticenter observation studyVATS, video-assisted thoracic surgery

Identifiers

PMID36004184
PMCPMC9390273
OpenAlexW3195070521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.