Evidence map›Paper›PMID 36004130›Full record

ArticleJTCVS open2021

Stentless valves for bicuspid and tricuspid aortic valve disease.

Bailey Brown, Tan Le, Aroma Naeem, Aroosa Malik, Elizabeth L Norton, Xiaoting Wu, Himanshu J Patel, G Michael Deeb, Karen M Kim, Bo Yang

Open access · goldAbstract read
In one paragraph

Article in JTCVS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Bailey BrownDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Tan LeDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Aroma NaeemDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Aroosa MalikDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Elizabeth L NortonCreighton University School of Medicine, Omaha, Neb.
Xiaoting WuDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Himanshu J PatelDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
G Michael DeebDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Karen M KimDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Bo YangDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Michigan Medicine · USCreighton University · US

Funding

Therapeutic Insights into Loeys-Dietz Syndrome using Humanized ModelsR01HL151776 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Bo Yang · 2020 to 2026
$4.2M
Define the mechanisms of aortopathy in bicuspid aortic valve patientsR01HL141891 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2018 to 2022
$3.5M
Effect of mutations in the TGF-beta pathway genes on smooth muscle cell differentiation using patient derived iPSCs.K08HL130614 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YANG, BO · 2016 to 2020
$848k
NHLBI NIH HHS K08 HL130614NHLBI NIH HHS R01 HL141891NHLBI NIH HHS R01 HL151776
6 · The paper itself

Abstract

Objective: To determine long-term survival and reoperation rate in patients with a bicuspid aortic valve (BAV) and patients with a tricuspid aortic valve (TAV) after stentless aortic valve replacement (AVR)/aortic root replacement (ARR). Methods: Between 1992 and 2014, 1293 patients underwent first AVR/ARR with a stentless aortic valve using the modified inclusion operating technique, including 741 patients with a TAV and 552 with a BAV. Using propensity scoring with 26 variables, 330 matched pairs were identified with AVR with or without ascending aorta/arch replacement. Data were obtained through chart review, surveys, and the National Death Index. Results: Patient demographics were similar in the propensity score-matched groups. Both groups had similar cardiopulmonary bypass, cross-clamp, and hypothermia circulatory arrest times, cerebral protection strategies, and rate of aortic arch replacement. The median size of implanted valves was similar (BAV: 27 mm [range, 25-29 mm] vs TAV: 27 mm [range, 25-27 mm]). Compared with the TAV group, the BAV group had a shorter hospital stay (6 days vs 7 days; Conclusions: The BAV patients had better long-term survival but a higher reoperation rate compared with TAV patients after stentless AVR. Our findings suggest caution in the use of bioprostheses for BAV patients.

Indexed as

aortic valve replacementAVR, aortic valve replacementBAV, bicuspid aortic valvebicuspid aortic valvebioprosthesisCI, confidence intervalHR, hazard ratiolong-term survivalNDI, National Death IndexOR, odds ratioreoperationSAVR, surgical aortic valve replacementstentless valveTAVR, transcatheter aortic valve replacementTAV, tricuspid aortic valve

Identifiers

PMID36004130
PMCPMC9390591
OpenAlexW3203487419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.