ArticleJTCVS open2021
Outcomes after resection of primary cardiac sarcoma.
Article in JTCVS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Multimodality treatment and survival in primary cardiac malignancies: evidence from competing-risk and machine learning analyses.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Staged Cesarean and Cardiac Surgery for Recurrent Left Atrial Myxofibrosarcoma in Pregnancy.JACC. Case reports · 2026Article
- Circumferential Resection of the Right Atrium to Excise Angiosarcoma.JACC. Case reports · 2026Article
- Cardiac intimal sarcoma presenting as basilar artery occlusion treated with tenecteplase and thrombectomy: a case report.Frontiers in cardiovascular medicine · 2026Article
- Long-Term Survival after Repeat Resection and Multimodal Therapy for Primary Cardiac Angiosarcoma: A Case Report.Surgical case reports · 2026Article
- Surgical Management of Primary and Metastatic Cardiac Malignancies: A 20-Year Single-Center Experience.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- Surgical resection of a primary cardiac angiosarcoma and reconstruction of involved right atrium.Journal of surgical case reports · 2026Article
- Primary Cardiac Sarcomas: Clinical Characteristics, Management, and Outcomes at a Spanish National Reference Center.Cancers · 2025Article
- 1-Month Relapse of Undifferentiated Sarcoma in the Left Atrium.JACC. Case reports · 2025Article
- Primary Cardiac Lymphoma Masquerading as a Pericardial Mass: Imaging, 3D Printing, and Surgical Management.JACC. Case reports · 2025Article
- Article
- Primary cardiac angiosarcoma: A clinical report of 1 case and review of the literature.Medicine · 2025Review
- Primary cardiac angiosarcoma: a case report.Frontiers in oncology · 2025Article
- From dyspnea to diagnosis, unmasking undifferentiated cardiac sarcoma: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Article
- Primary cardiac sarcoma: demographics, genomic study correlation, and survival benefits of surgery with adjuvant therapy in U.S. population.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Article
- Multimodality Imaging in the Evaluation and Management of a Right Atrial Mass.CASE (Philadelphia, Pa.) · 2024Article
- Rare Case Report: Left Atrial Sarcoma Obstructing the Left Ventricular Inflow.Journal of clinical medicine · 2023Article
- Reduced Risk of All-Cause, Cancer-, and Cardiovascular Disease-Related Mortality among Patients with Primary Malignant Cardiac Tumors Receiving Chemotherapy in the United States.Current oncology (Toronto, Ont.) · 2023Article
- Geographic variation in malignant cardiac tumors and their outcomes: SEER database analysis.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the outcomes of surgical resection of malignant primary cardiovascular tumors. Methods: From 1983 to 2018, 32 patients underwent surgical resection of malignant primary cardiovascular sarcoma at Cleveland Clinic. Mean age was 48 ± 15 years, and 19 (59%) were women. Outcomes are compared between those with complete resection and those without, and in relation to primary location. Results: The most common histologic subtypes were angiosarcoma (n = 8 [25%]) and high-grade undifferentiated sarcoma (n = 7 [22%]). Fourteen (44%) involved the left heart, 9 (28%) the right heart, 8 (25%) the pulmonary arteries, and 1 (3%) the aorta. There was clinical evidence of isolated extracardiac metastases in 8 (25%). Six (19%) patients were deemed unresectable at surgery, undergoing biopsy and palliative debulking followed by referral for definitive chemotherapy and/or radiation. The remaining 26 (81%) patients underwent 31 tumor resections with curative intent. Seven (22%) patients had previously undergone a resection or biopsy at another institution. There were 10 second-time resections, 2 third-time resections, 1 fourth-time resection, and no operative mortalities. Median survival was 3 years, with estimated survival at 6 months and 1, 5, and 10 years of 90%, 73%, 31%, and 17%, respectively. Of the 8 (25%) who were considered disease-free following surgery, 4 experienced recurrences during follow-up. Conclusions: Primary cardiac sarcoma continues to be a challenging disease with poor prognosis. Aggressive resection with curative intent, frequent surveillance for local and distant recurrence, and systemic and local multimodality treatment optimizes outcomes.
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