ArticleContrast media & molecular imaging2022
Study on the Prognosis Effect of Traditional Chinese Medicine Treatment in DR Patients Based on the Perspective of Network Pharmacology.
Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Non-invasive pharmacological advances in early retinopathy treatment: bioactive herbal compounds, polymer delivery systems, and computational bioprospecting of functional targets.Pharmacological reports : PR · 2026Review
- Network Pharmacology Analysis, Molecular Docking Integrated Experimental Verification Reveal the Mechanism ofCurrent issues in molecular biology · 2024Article
- Total Alkaloids ofJournal of inflammation research · 2024Article
- Key ingredients inFrontiers in plant science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes damages the eye in many ways, but the most common eye complication is retinopathy. Of the 246 million people with diabetes worldwide, about 30% will be at risk of developing diabetic retinopathy. In addition to impairing vision, the presence of diabetic retinopathy also means an increased risk of life-threatening systemic vascular complications. To prevent the occurrence and development of diabetic retinopathy, the research and development of new drugs for diabetic retinopathy is the primary task. Because of its characteristics of holistic view and dialectical view, traditional Chinese medicine has a good effect in the treatment of complex diseases. However, due to the characteristics of complex components, numerous targets, and synergistic effects that are important, and its compound prescriptions, the modernization of traditional Chinese medicine has been hindered. The rise of network pharmacology in recent years provides a good opportunity for the development of traditional Chinese medicine. Network pharmacology aims to explore the relationship between drugs and diseases from a holistic perspective, discover drug targets, and guide the development of new drugs. In terms of methodology, network pharmacology has the characteristics of integrity and systematicness, which just coincides with the principle of consultation in traditional Chinese medicine. In this paper, from the perspective of the application of traditional Chinese medicine, TCMSP software was used to retrieve the active ingredients in traditional Chinese medicine, and the corresponding targets of the active ingredients were obtained. We then performed GO annotation analysis and KEGG pathway analysis on the targets using DAVID software. We further used Cytoscape software to build an active ingredient-target-pathway network model. Through network pharmacology research, it has been shown that Fufang Xueshuantong may treat diabetic retinopathy through multiple pathways such as intravascular growth factor signaling pathway, mitogen-activated protein kinase signaling pathway, and Toll sample receptor signaling pathway, reflecting the multicomponent traditional Chinese medicine compound and multitarget and multichannel characteristics. The research in this paper provides a theoretical basis for the pharmacological mechanism of traditional Chinese medicine in the treatment of diabetic retinopathy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.