Evidence map›Paper›PMID 36003940›Full record

ReviewFrontiers in microbiology2022

Common themes in antimicrobial and anticancer drug resistance.

Mariana Carmen Chifiriuc, Roxana Filip, Marian Constantin, Gratiela Gradisteanu Pircalabioru, Coralia Bleotu, Liliana Burlibasa, Elena Ionica, Nicolae Corcionivoschi, Grigore Mihaescu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

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  15. Biomineral-Based Composite Materials in Regenerative Medicine.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mariana Carmen ChifiriucFaculty of Biology, University of Bucharest, Bucharest, Romania.
Roxana FilipFaculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, Suceava, Romania.
Marian ConstantinInstitute of Biology, Bucharest, Romania.
Gratiela Gradisteanu PircalabioruFaculty of Biology, University of Bucharest, Bucharest, Romania.
Coralia BleotuStefan S. Nicolau Institute of Virology, Bucharest, Romania.
Liliana BurlibasaFaculty of Biology, University of Bucharest, Bucharest, Romania.
Elena IonicaFaculty of Biology, University of Bucharest, Bucharest, Romania.
Nicolae CorcionivoschiBacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast, United Kingdom.
Grigore MihaescuFaculty of Biology, University of Bucharest, Bucharest, Romania.
University of Bucharest · ROAcademy of Romanian Scientists · ROAgri Food and Biosciences Institute · GBŞtefan cel Mare University of Suceava · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial and anticancer drug resistance represent two of the main global challenges for the public health, requiring immediate practical solutions. In line with this, we need a better understanding of the origins of drug resistance in prokaryotic and eukaryotic cells and the evolutionary processes leading to the occurrence of adaptive phenotypes in response to the selective pressure of therapeutic agents. The purpose of this paper is to present some of the analogies between the antimicrobial and anticancer drug resistance. Antimicrobial and anticancer drugs share common targets and mechanisms of action as well as similar mechanisms of resistance (e.g., increased drug efflux, drug inactivation, target alteration, persister cells' selection, protection of bacterial communities/malignant tissue by an extracellular matrix, etc.). Both individual and collective stress responses triggered by the chemotherapeutic agent involving complex intercellular communication processes, as well as with the surrounding microenvironment, will be considered. The common themes in antimicrobial and anticancer drug resistance recommend the utility of bacterial experimental models for unraveling the mechanisms that facilitate the evolution and adaptation of malignant cells to antineoplastic drugs.

Indexed as

efflux pumpsgut microbiotamicrobial biofilmsmutator phenotypepersister cellsstress response

Identifiers

PMID36003940
PMCPMC9393787
OpenAlexW4290636015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.