Evidence map›Paper›PMID 36003937›Full record

ReviewFrontiers in microbiology2022

Expanding the chemical diversity of M13 bacteriophage.

Grace L Allen, Ashley K Grahn, Katerina Kourentzi, Richard C Willson, Sean Waldrop, Jiantao Guo, Brian K Kay

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Phage Display as a Promising Platform for Peptide Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Chemical reviews · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Encoding Noncanonical Amino Acids into Phage Displayed Proteins.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Grace L AllenTango Biosciences, Inc., Chicago, IL, United States.
Ashley K GrahnTango Biosciences, Inc., Chicago, IL, United States.
Katerina KourentziDepartment of Chemical and Biomolecular Engineering, University of Houston, Houston, TX, United States.
Richard C WillsonDepartment of Chemical and Biomolecular Engineering, University of Houston, Houston, TX, United States.
Sean WaldropDepartment of Chemistry, University of Nebraska at Lincoln, Lincoln, NE, United States.
Jiantao GuoDepartment of Chemistry, University of Nebraska at Lincoln, Lincoln, NE, United States.
Brian K KayTango Biosciences, Inc., Chicago, IL, United States.
Tango Therapeutics (United States) · USUniversity of Houston · USUniversity of Nebraska–Lincoln · US

Funding

Targeted mass spectrometry approaches to understand CART processing and recepter interactionsP20GM113126 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI GUO, JIANTAO · 2016 to 2025
$20.8M
Building a pipeline to generate affinity reagents to phosphothreonine epitopesR43GM146514 · NIGMS · TANGO BIOSCIENCES, INC. · PI KAY, BRIAN KENNETH · 2022 to 2022
$223k
NIGMS NIH HHS P20 GM113126NIGMS NIH HHS R43 GM146514
6 · The paper itself

Abstract

Bacteriophage M13 virions are very stable nanoparticles that can be modified by chemical and genetic methods. The capsid proteins can be functionalized in a variety of chemical reactions without loss of particle integrity. In addition, Genetic Code Expansion (GCE) permits the introduction of non-canonical amino acids (ncAAs) into displayed peptides and proteins. The incorporation of ncAAs into phage libraries has led to the discovery of high-affinity binders with low nanomolar dissociation constant (

Indexed as

antibody fragmentsbioconjugationcombinatorial peptide librariescross-linkingcyclizationpeptidephage-displaystop codon suppression

Identifiers

PMID36003937
PMCPMC9393631
OpenAlexW4290617263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.