Evidence map›Paper›PMID 36003770›Full record

ReviewFrontiers in oncology2022

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles.

Gábor Valcz, Beáta Újvári, Edit I Buzás, Tibor Krenács, Sándor Spisák, Ágnes Kittel, Zsolt Tulassay, Péter Igaz, István Takács, Béla Molnár

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  8. Revisiting Clonal Evolution Through the Light of Retrotransposons.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
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  12. Reduced circulating CD63Cardiovascular diabetology · 2024
    Article
  13. Review
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Gábor ValczMTA-SE Molecular Medicine Research Group, Eötvös Loránd Research Network, Budapest, Hungary.
Beáta ÚjváriSchool of Life and Environmental Sciences, Centre for Integrative Ecology, Deakin University, Waurn Ponds, VIC, Australia.
Edit I BuzásDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
Tibor Krenács1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Sándor SpisákInstitute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
Ágnes KittelInstitute of Experimental Medicine, Eötvös Loránd Research Network, Budapest, Hungary.
Zsolt TulassayMTA-SE Molecular Medicine Research Group, Eötvös Loránd Research Network, Budapest, Hungary.
Péter IgazMTA-SE Molecular Medicine Research Group, Eötvös Loránd Research Network, Budapest, Hungary.
István TakácsDepartment of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary.
Béla MolnárMTA-SE Molecular Medicine Research Group, Eötvös Loránd Research Network, Budapest, Hungary.
Semmelweis University · HUHungarian Research Network · HUDeakin University · AUHUN-REN Research Centre for Natural Sciences · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The basis of the conventional gene-centric view on tumor evolution is that vertically inherited mutations largely define the properties of tumor cells. In recent years, however, accumulating evidence shows that both the tumor cells and their microenvironment may acquire external, non-vertically inherited genetic properties

Indexed as

cell-cell communicationexosomesextracellular vesicleshorizontal gene transfertumor evolution

Identifiers

PMID36003770
PMCPMC9393732
OpenAlexW4290612744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.