Evidence map›Paper›PMID 36003738›Full record

ArticleJTCVS open2021

Effect of untreated carotid artery stenosis at the time of isolated coronary artery bypass grafting.

Nicholas R Hess, Arman Killic, Derek R Serna-Gallegos, Forozan Navid, Yisi Wang, Floyd Thoma, Ibrahim Sultan

Open access · goldAbstract read
In one paragraph

Article in JTCVS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nicholas R HessDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Arman KillicDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Derek R Serna-GallegosDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Forozan NavidDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Yisi WangDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Floyd ThomaDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
Ibrahim SultanDivision of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pa.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe carotid artery stenosis (sCAS) is frequently discovered at the time of evaluation for coronary arterial revascularization. However, there has been controversy regarding the optimal management of sCAS. This study evaluated the potential effects of untreated sCAS at time of coronary artery bypass grafting (CABG) in contemporary practice. Methods: This was a retrospective study from a multihospital healthcare system including patients undergoing isolated CABG between 2011 and 2018. Patients were stratified by the presence of sCAS (≥80% stenosis) in at least 1 carotid artery. Perioperative and 5-year stroke were compared, and multivariable analysis was used to identify risk-adjusted predictors of stroke and mortality. Results: A total of 5475 patients were included, 459 (8.4%) with sCAS and 5016 (91.6%) without sCAS. Patients with sCAS experienced more frequent perioperative stroke (4.4% vs 1.2%; Conclusions: This contemporary analysis of CABG procedures reveals that concurrent sCAS continues to confer a significant stroke risk, especially in those with history of previous stroke. Although whether sCAS lesions are responsible for most strokes is unclear, they likely serve as a surrogate for other stroke risk factors.

Indexed as

CABG, coronary artery bypass graftingcarotid artery stenosiscoronary artery bypass graftingcoronary artery diseaseCVA, cerebrovascular accidentMAP, mean arterial pressuresCAS, severe carotid artery stenosisSTS, Society of Thoracic Surgeons

Identifiers

PMID36003738
PMCPMC9390650
OpenAlexW3179266858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.