Evidence map›Paper›PMID 36003629›Full record

ReviewFrontiers in public health2022

SARS-CoV-2 pre-exposure prophylaxis: A potential COVID-19 preventive strategy for high-risk populations, including healthcare workers, immunodeficient individuals, and poor vaccine responders.

Jing Ouyang, Silvere D Zaongo, Vijay Harypursat, Xiaofang Li, Jean-Pierre Routy, Yaokai Chen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jing OuyangClinical Research Center, Chongqing Public Health Medical Center, Chongqing, China.
Silvere D ZaongoClinical Research Center, Chongqing Public Health Medical Center, Chongqing, China.
Vijay HarypursatClinical Research Center, Chongqing Public Health Medical Center, Chongqing, China.
Xiaofang LiClinical Research Center, Chongqing Public Health Medical Center, Chongqing, China.
Jean-Pierre RoutyInfectious Diseases and Immunity in Global Health Program, Research Institute, McGill University Health Centre, Montréal, QC, Canada.
Yaokai ChenClinical Research Center, Chongqing Public Health Medical Center, Chongqing, China.
Chongqing Public Health Medical Center · CNMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unprecedented worldwide spread of SARS-CoV-2 has imposed severe challenges on global health care systems. The roll-out and widespread administration of COVID-19 vaccines has been deemed a major milestone in the race to restrict the severity of the infection. Vaccines have as yet not entirely suppressed the relentless progression of the pandemic, due mainly to the emergence of new virus variants, and also secondary to the waning of protective antibody titers over time. Encouragingly, an increasing number of antiviral drugs, such as remdesivir and the newly developed drug combination, Paxlovid

Indexed as

COVID-19HIV InfectionsAntiviral AgentsCOVID-19 VaccinesHealth PersonnelHumansRisk FactorsSARS-CoV-2Antiviral AgentsCOVID-19 VaccinesCOVID-19high-risk populationmolnupiravirpre-exposure prophylaxis (PrEP)remdesivir

Identifiers

PMID36003629
PMCPMC9393547
OpenAlexW4290612352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.