Evidence map›Paper›PMID 36003624›Full record

ArticleTherapeutic advances in drug safety2022

Patients' attitudes toward deprescribing and their experiences communicating with clinicians and pharmacists.

Kaylee M Lukacena, James W Keck, Patricia R Freeman, Nancy Grant Harrington, Mark J Huffmyer, Daniela C Moga

Abstract read
In one paragraph

Article in Therapeutic advances in drug safety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Challenges and possibilities of enabling person-centred engagement in medication safety with older people living at home.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026
    Article
  7. Article
  8. Engaging Patients in Discussions About Medication Deprescribing.Journal of general internal medicine · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaylee M LukacenaCenter for Social and Behavioral Science, Office of the Vice Chancellor for Research and Innovation, University of Illinois Urbana-Champaign, Urbana, IL, USA.
James W KeckDepartment of Family and Community Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
Patricia R FreemanDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Nancy Grant HarringtonDepartment of Communication, College of Communication and Information, University of Kentucky, Lexington, KY, USA.
Mark J HuffmyerDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA.
Daniela C MogaDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, USA. Department of Epidemiology, College of Public Health, University of Kentucky, Lexington, KY, USA.ORCID https://orcid.org/0000-0002-3648-8197

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
INtervention for Cognitive Reserve Enhancement in delaying the onset of Alzheimer’s Symptomatic Expression: The INCREASE studyR01AG054130 · NIA · UNIVERSITY OF KENTUCKY · PI JICHA, GREGORY A, MOGA, DANIELA CLAUDIA · 2016 to 2020
$2.0M
NCATS NIH HHS UL1 TR001998NIA NIH HHS R01 AG054130
6 · The paper itself

Abstract

Purpose: Developing effective deprescribing interventions relies on understanding attitudes, beliefs, and communication challenges of those involved in the deprescribing decision-making process, including the patient, the primary care clinician, and the pharmacist. The objective of this study was to assess patients' beliefs and attitudes and identify facilitators of and barriers to deprescribing. Methods: As part of a larger study, we recruited patients ⩾18 years of age taking ⩾3 chronic medications. Participants were recruited from retail pharmacies associated with the University of Kentucky HealthCare system. They completed an electronic survey that included demographic information, questions about communication with their primary care clinician and pharmacists, and the revised Patients' Attitudes Toward Deprescribing (rPATD) questionnaire. Results: Our analyses included 103 participants ( Conclusion: Adults taking ⩾3 chronic medications expressed high willingness to accept deprescribing of medications when their doctor said it was possible. Targeted strategies to facilitate communication within the patient-primary care clinician-pharmacist triad that consider patient characteristics such as age and education level may be necessary ingredients for developing successful deprescribing interventions. Plain Language Summary:

Indexed as

communicationdeprescribinginappropriate medicationspatientpolypharmacy

Identifiers

PMID36003624
PMCPMC9393353

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.