Evidence map›Paper›PMID 36003515›Full record

ArticleFrontiers in pharmacology2022

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation.

Duncan C Humphries, Ross Mills, Cecilia Boz, Brian J McHugh, Nikhil Hirani, Adriano G Rossi, Anders Pedersen, Hans T Schambye, Robert J Slack, Hakon Leffler and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Journal of medicinal chemistry · 2025
    Article
  3. Article
  4. Mechanical stretch promotes sustained proliferation and inflammation in developing human airway smooth muscle.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  5. Article
  6. Review
  7. Current and novel biomarkers in cardiogenic shock.European journal of heart failure · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Mesenchymal ovarian cancer cells promote CD8NPJ systems biology and applications · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Duncan C HumphriesCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Ross MillsCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Cecilia BozCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Brian J McHughCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Nikhil HiraniCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Adriano G RossiCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Anders PedersenGalecto Inc, Copenhagen, Denmark.
Hans T SchambyeGalecto Inc, Copenhagen, Denmark.
Robert J SlackGalecto Inc, Stevenage, United Kingdom.
Hakon LefflerDepartment of Laboratory Medicine, Lund University, Lund, Sweden.
Ulf J NilssonDepartment of Chemistry, Lund University, Lund, Sweden.
Wei WangDepartment of Asthma, Allergy and Respiratory Science, King's College London, Guy's Hospital, London, United Kingdom.
Tariq SethiGalecto Inc, Copenhagen, Denmark.
Alison C MackinnonCentre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Centre for Inflammation Research · GBUniversity of Edinburgh · GBGalecto (Denmark) · DKLund University · SEGuy's Hospital · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute lung injurycytokinegalectin-3LPSneutrophiils

Identifiers

PMID36003515
PMCPMC9393216
OpenAlexW4290565378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.