Evidence map›Paper›PMID 36003507›Full record

ArticleFrontiers in pharmacology2022

Allyl methyl trisulfide protected against LPS-induced acute lung injury in mice via inhibition of the NF-κB and MAPK pathways.

Shuo Wang, Jinqian Liu, Jing Dong, Zongqiang Fan, Fugui Wang, Ping Wu, Xiaojing Li, Ruirui Kou, Fang Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  10. Rhein-attenuates LPS-induced acute lung injury via targeting NFATc1/Trem2 axis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shuo WangSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Jinqian LiuSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Jing DongSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Zongqiang FanSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Fugui WangSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Ping WuSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Xiaojing LiSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Ruirui KouSchool of Public Health, Shandong University, Jinan, Shandong, China.
Fang ChenSchool of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, China.
Liaocheng University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allyl methyl trisulfide (AMTS) is one major lipid-soluble organosulfur compound of garlic. Previous studies have reported the potential therapeutic effect of garlic on acute lung injury (ALI) or its severe condition acute respiratory distress syndrome (ARDS), but the specific substances that exert the regulatory effects are still unclear. In this study, we investigate the protective effects of AMTS on lipopolysaccharide (LPS)-induced ALI mice and explored the underlying mechanisms. In

Indexed as

acute lung injuryallyl methyl trisulfideinflammatory mediatorsmapksNF-κB

Identifiers

PMID36003507
PMCPMC9394683
OpenAlexW4290565767

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.